Literature DB >> 26355741

Correction: Prevalence and Molecular Characterization of Glucose-6-Phosphate Dehydrogenase Deficiency at the China-Myanmar Border.

Qing Li, Fang Yang, Rong Liu, Lan Luo, Yuling Yang, Lu Zhang, Huaie Liu, Wen Zhang, Zhixiang Fan, Zhaoqing Yang, Liwang Cui, Yongshu He.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0134593.].

Entities:  

Year:  2015        PMID: 26355741      PMCID: PMC4565689          DOI: 10.1371/journal.pone.0138038

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


There are errors in the Results section of this article. In fifth sentence of the “Identification of G6PD mutations” subsection, 9.7% should be 89.7%. The correct sentence is: Of these 87 cases, the Mahidol 487G>A type was the most predominant, occurring in 89.7% (78/87) of the subjects. In the eighth sentence of the same subsection, 58.0% should be 48%. The correct sentence is: In addition, the silent mutation 1311C>T and the intron 11 mutation IVS11nt93T>C co-occurred in 48% (95/198) of the tested individuals (Table 2).
Table 2

Prevalence [n (%)] of G6PD variants in 198 unrelated G6PD-deficient participants .

MutationsAmino Acid SubstitutionTotal (n = 198)Female (n = 147)Male (n = 51) P *
HomozygousHeterozygous
Nonsynonymous mutations
Chinese 4 392G>TG131V1 (0.5%)01 (0.7%)0
Mahidol 487G>AG163S76 (38.4%)5 (3.4%)52 (35.4%)19 (37.3%)0.870
Viangchan 871G>AV291M1 (0.5%)01 (0.7%)0
Canton 1376G>TR459L1 (0.5%)01 (0.7%)0
Kaiping 1388G>AR463H6 (3.0%)1 (0.7%)3 (2.0%)2 (3.9%)0.000
Mahidol/ViangchanG163S/V291M1 (0.5%)01 (0.7%)0
Mahidol/KaipingG163S/R463H1 (0.5%)01 (0.7%)0
Synonymous mutations
1311C >T/93 T>C** Silent mutations95 (48.0%)9 (6.1%)74 (50.3%)12 (23.5%)0.000
Unknown 42 (21.2%)24 (16.3%)18 (35.3%)

# The mutations Gaohe 95 A >G (H32R), Coimbra 592 C >T (R198C), Chinese 5 1024C >T (L342F), and Union 1360 C>T (R454C) were genotyped and not found in this study population.

*P value shows the differences in the prevalence of major G6PD deficiency variants between males and females compared using the Fisher’s exact test (two-tailed).

** 24 and 2 of these double silent mutations co-occurred in females heterozygous for the Mahidol and Kaiping mutations, respectively.

In addition, there is an error in Table 2: The value 18(35.3%) should not appear in the “Heterozygous” column but in the “Male (n = 51)” column. Please see the correct Table 2 here. # The mutations Gaohe 95 A >G (H32R), Coimbra 592 C >T (R198C), Chinese 5 1024C >T (L342F), and Union 1360 C>T (R454C) were genotyped and not found in this study population. *P value shows the differences in the prevalence of major G6PD deficiency variants between males and females compared using the Fisher’s exact test (two-tailed). ** 24 and 2 of these double silent mutations co-occurred in females heterozygous for the Mahidol and Kaiping mutations, respectively.
  1 in total

1.  Prevalence and Molecular Characterization of Glucose-6-Phosphate Dehydrogenase Deficiency at the China-Myanmar Border.

Authors:  Qing Li; Fang Yang; Rong Liu; Lan Luo; Yuling Yang; Lu Zhang; Huaie Liu; Wen Zhang; Zhixiang Fan; Zhaoqing Yang; Liwang Cui; Yongshu He
Journal:  PLoS One       Date:  2015-07-30       Impact factor: 3.240

  1 in total
  2 in total

1.  Seasonal dynamics and microgeographical spatial heterogeneity of malaria along the China-Myanmar border.

Authors:  Yue Hu; Guofa Zhou; Yonghua Ruan; Ming-Chieh Lee; Xin Xu; Shuang Deng; Yao Bai; Jie Zhang; James Morris; Huaie Liu; Ying Wang; Qi Fan; Peipei Li; Yanrui Wu; Zhaoqing Yang; Guiyun Yan; Liwang Cui
Journal:  Acta Trop       Date:  2016-01-23       Impact factor: 3.112

2.  Massively parallel sequencing uncovered disease-associated variant spectra of glucose-6-phosphate dehydrogenase deficiency, phenylketonuria and galactosemia in Vietnamese pregnant women.

Authors:  Tat-Thanh Nguyen; Quang-Thanh Le; Diem-Tuyet Thi Hoang; Huu Du Nguyen; Thi Minh Thi Ha; My-Nhi Ba Nguyen; Thanh-Thuy Thi Ta; Nhat Thang Tran; Thu Huong Nhat Trinh; Kim Phuong Thi Doan; Duc Tam Lam; Son Tra Thi Tran; Thanh Xuan Nguyen; Hong-Thinh Le; Van Tuan Ha; Manh Hoan Nguyen; Ba-Liem Kim Le; My Linh Duong; Trung Ha Pham; Anh Tuan Tran; Xuan Lan Thi Phan; Thanh Liem Huynh; Lan-Phuong Thi Nguyen; Thanh Binh Vo; Duy-Khang Nguyen Le; Ngoc Nhu Thi Tran; Quynh Nhu Thi Tran; Yen-Linh Thi Van; Bich-Ngoc Thi Huynh; Thanh-Phương Thi Nguyen; Trang Thi Dao; Lan Phuong Thi Nguyen; Truong-Giang Vo; Thanh-Thuy Thi Do; Dinh-Kiet Truong; Hung Sang Tang; Minh-Duy Phan; Hoai-Nghia Nguyen; Hoa Giang
Journal:  Mol Genet Genomic Med       Date:  2022-05-03       Impact factor: 2.473

  2 in total

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