Øistein Hovde1, Milada C Småstuen, Marte L Høivik, Tomm Bernklev, Gert Huppertz-Hauss, Ole Høie, Jørgen Jahnsen, Njaal Stray, Magne Henriksen, Inger C Solberg, Bjørn A Moum. 1. *Department of Gastroenterology, Innlandet Hospital Trust, Gjøvik, Norway, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; †Department of Biostatistics, Faculty of Medicine, University of Oslo, Oslo, Norway; ‡Department of Gastroenterology, Oslo University Hospital, Oslo, Norway; §Department for Research and Development, Telemark Hospital, Skien, Norway, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; ‖Department of Gastroenterology, Telemark Hospital, Skien, Skien, Norway; ¶Department of Internal Medicine, Sørlandet Hospital, Arendal, Norway; **Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; ††Department of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway; ‡‡Department of Gastroenterology, Østfold Hospital, Fredrikstad, Norway; and §§Department of Gastroenterology, Oslo University Hospital, Oslo, Norway, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Abstract
BACKGROUND: The best way to obtain knowledge about the natural history, including mortality, of ulcerative colitis (UC) is to conduct a longitudinal, population-based, prospective study. The aims of this study were to calculate the mortality rates and causes of death in patients with UC. METHODS: A prospective, population-based, longitudinal cohort study was conducted in South-Eastern Norway. A total of 519 patients (51.4% men) with UC were included over a 4-year period. A gastroenterologist from a university hospital reviewed the clinical information of all of the patients. Mortality data were retrieved from the Cause of Death Registry and from Statistics Norway. RESULTS: No statistically significant increases in total mortality or cause-specific mortality between the patients with UC and the controls were found. CONCLUSIONS: The present 20-year population-based cohort study revealed a good prognosis regarding the mortality, which partially might be explained by the patients' coverage by a generally well-functioning health care system.
BACKGROUND: The best way to obtain knowledge about the natural history, including mortality, of ulcerative colitis (UC) is to conduct a longitudinal, population-based, prospective study. The aims of this study were to calculate the mortality rates and causes of death in patients with UC. METHODS: A prospective, population-based, longitudinal cohort study was conducted in South-Eastern Norway. A total of 519 patients (51.4% men) with UC were included over a 4-year period. A gastroenterologist from a university hospital reviewed the clinical information of all of the patients. Mortality data were retrieved from the Cause of Death Registry and from Statistics Norway. RESULTS: No statistically significant increases in total mortality or cause-specific mortality between the patients with UC and the controls were found. CONCLUSIONS: The present 20-year population-based cohort study revealed a good prognosis regarding the mortality, which partially might be explained by the patients' coverage by a generally well-functioning health care system.
Authors: Joseph D Feuerstein; Thomas Curran; Michael Alosilla; Thomas Cataldo; Kenneth R Falchuk; Vitaliy Poylin Journal: Dig Dis Sci Date: 2018-01-20 Impact factor: 3.199