Literature DB >> 26352730

Dual functionality of phosphonic-acid-appended phthalocyanines: inhibitors of urokinase plasminogen activator and anticancer photodynamic agents.

N Venkatramaiah1, Patrícia M R Pereira, Filipe A Almeida Paz, Carlos A F Ribeiro, Rosa Fernandes, João P C Tomé.   

Abstract

Phthalocyanines (Pcs) bearing phosphonic acid groups at the periphery exhibit a potential photodynamic effect to induce phototoxicity on human bladder cancer epithelial cells (UM-UC-3). In vitro photophysical and biological studies show high intrinsic ability to inhibit the activity of urokinase plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9).

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Year:  2015        PMID： 26352730     DOI： 10.1039/c5cc06561e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Peripherally Crowded Cationic Phthalocyanines as Efficient Photosensitizers for Photodynamic Therapy.

Authors:  Marie Halaskova; Asma Rahali; Verónica Almeida-Marrero; Miloslav Machacek; Radim Kucera; Bassem Jamoussi; Tomás Torres; Veronika Novakova; Andrés de la Escosura; Petr Zimcik
Journal:  ACS Med Chem Lett       Date:  2021-03-01       Impact factor: 4.345

2.  Crystal structure of a compact three-dimensional metal-organic framework based on Cs+ and (4,5-di-cyano-1,2-phenyl-ene)bis-(phospho-nic acid).

Authors:  Ricardo F Mendes; Nutalapati Venkatramaiah; João P C Tomé; Filipe A Almeida Paz
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2016-11-15

3.  Selective Detection of Trinitrophenol by Amphiphilic Dimethylaminopyridine-Appended Zn(II)phthalocyanines at the Near-Infrared Region.

Authors:  S Kasthuri; Pratiksha Gawas; Samarendra Maji; N Veeraiah; N Venkatramaiah
Journal:  ACS Omega       Date:  2019-04-03
  3 in total

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