| Literature DB >> 2635167 |
N Casado, F Rodriguez-Caabeiro, A Jiménez, A Criado, C de Armas.
Abstract
The in vitro effects of levamisole and ivermectin against Echinococcus granulosus protoscoleces were studied by means of light and electron microscopy. Both drugs had a protoscolicidal activity that increased proportionally with increasing concentrations of the drugs. Ivermectin showed the more rapid effects and caused contraction and paralysis of protoscoleces. A paralyzing effect was also observed with levamisole, followed by irreversible tissue vacuolation leading to death.Entities:
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Year: 1989 PMID: 2635167 DOI: 10.1016/0020-7519(89)90125-2
Source DB: PubMed Journal: Int J Parasitol ISSN: 0020-7519 Impact factor: 3.981