| Literature DB >> 26350960 |
Abstract
Stem cells are remarkable, and stem cell-based tissue engineering is an emerging field of biomedical science aiming to restore damaged tissue or organs. In dentistry and reconstructive facial surgery, it is of great interest to restore lost teeth or craniofacial bone defects using stem cell-mediated therapy. In the craniofacial region, various stem cell populations have been identified with regeneration potential. In this review, we provide an overview of the current knowledge concerning the various types of tooth- and craniofacial bone-related stem cells and discuss their in vivo identities and regulating mechanisms. © International & American Associations for Dental Research 2015.Entities:
Keywords: Gli1 protein; hedgehogs; mesenchymal stromal cells; neural crest; skull; stem cell niche
Mesh:
Year: 2015 PMID: 26350960 PMCID: PMC4622324 DOI: 10.1177/0022034515603972
Source DB: PubMed Journal: J Dent Res ISSN: 0022-0345 Impact factor: 6.116