Literature DB >> 26350894

Clinical Burden and Nonpharmacologic Management of Nursing Facility Residents with Overactive Bladder and/or Urinary Incontinence.

Barbara J Zarowitz1, Carrie Allen, Terrence O'Shea, Eric Tangalos, Todd Berner, Joseph G Ouslander.   

Abstract

OBJECTIVE: To identify clinical characteristics of residents with a diagnosis of overactive bladder (OAB) and/or urinary incontinence (UI) to determine the prevalence of comorbidities, severe mobility impairment (SMI), moderate-to-severe cognitive impairment (MSCI), and a toileting program and the response to that program.
DESIGN: Cross-sectional retrospective analysis.
SETTING: Skilled nursing facilities. PATIENTS, PARTICIPANTS: Residents with a diagnosis of OAB and/or UI and an age range, and gender frequency-matched 1:1 control cohort without OAB and/or UI.
INTERVENTIONS: None. MAIN OUTCOME MEASURE(S): De-identified Minimum Data Set data 3.0 records (October 1, 2010, to September 30, 2012).
RESULTS: Of the 175,632 residents, 65% had a diagnosis of UI and 1% had a diagnosis of OAB. Those with UI and/or OAB were more likely to have MSCI (mean Brief Inventory of Mental Status score 10.2 ± 4.5 vs. 12.5 ± 3.6; P = 0.001) and SMI (49.4% vs. 26.4%; P < 0.001), multiple comorbid conditions, falls and falls with injury, hip fractures (5.5% vs. 4.9%; P < 0.001), urinary tract infections (21.4% vs. 16.5%; P = 0.001), and moisture-associated skin damage (5.2% vs. 2.6%; P = 0.001) than the control cohort. Toileting programs were attempted more often (17.0% vs. 5.1%; P < 0.001) in those with UI and/or OAB but were only minimally successful, with 4.2% having decreased wetness and 0.9% being completely dry.
CONCLUSION: Residents with UI and/or OAB exhibit a higher burden of MSCI, SMI, and comorbidities than do residents without these diagnoses. Nonpharmacologic therapies such as toileting programs should be a primary focus in the nursing facility.

Entities:  

Mesh:

Year:  2015        PMID: 26350894     DOI: 10.4140/TCP.n.2015.533

Source DB:  PubMed          Journal:  Consult Pharm        ISSN: 0888-5109


  6 in total

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Authors:  S Ida; R Kaneko; H Nagata; Y Noguchi; Y Araki; M Nakai; S Ito; K Imataka; K Murata
Journal:  J Nutr Health Aging       Date:  2019       Impact factor: 4.075

2.  CUA guideline on adult overactive bladder.

Authors:  Jacques Corcos; Mikolaj Przydacz; Lysanne Campeau; Gary Gray; Duane Hickling; Christiane Honeine; Sidney B Radomski; Lynn Stothers; Adrian Wagg; Frcp Lond
Journal:  Can Urol Assoc J       Date:  2017-05-09       Impact factor: 1.862

3.  Overactive Bladder Is Strongly Associated With Frailty in Older Individuals.

Authors:  Anne M Suskind; Kathryn Quanstrom; Shoujun Zhao; Mark Bridge; Louise C Walter; John Neuhaus; Emily Finlayson
Journal:  Urology       Date:  2017-05-11       Impact factor: 2.649

Review 4.  Anticholinergics for Overactive Bladder in Frail and Medically Complex Older People: The Case For.

Authors:  Adrian Wagg
Journal:  Drugs Aging       Date:  2018-09       Impact factor: 3.923

Review 5.  Overactive Bladder Prescribing Considerations: The Role of Polypharmacy, Anticholinergic Burden, and CYP2D6 Drug‒Drug Interactions.

Authors:  Matthew P Rutman; John R Horn; Diane K Newman; Richard G Stefanacci
Journal:  Clin Drug Investig       Date:  2021-03-12       Impact factor: 2.859

6.  Long-term treatment of older patients with overactive bladder using a combination of mirabegron and solifenacin: a prespecified analysis from the randomized, phase III SYNERGY II study.

Authors:  Elizabeth R Mueller; Rob van Maanen; Christopher Chapple; Paul Abrams; Sender Herschorn; Dudley Robinson; Matthias Stoelzel; Sang J Yoon; Salman Al-Shukri; Tomasz Rechberger; Christian Gratzke
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  6 in total

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