Literature DB >> 26349681

[Successful treatment of pediatric psoriasis with etanercept].

V V Gruben1, N Klossowski1, B Homey1, S Meller2.   

Abstract

Systemic treatment options for moderate to severe pediatric psoriasis are limited. Due to uncertainties regarding severe adverse events the majority of established systemic therapeutic drugs for adult psoriasis are not administered to children. In 2011 the TNF-α-inhibitor etanercept (Enbrel(®)) was approved as the first biological agent for the treatment of plaque psoriasis in pediatric patients. It is available for children from the age of 6 years and constitutes an effective and safe treatment option during childhood. Our report is based on the successful treatment of three boys with etanercept each at the age of 11 years.

Entities:  

Keywords:  Biological products; Plaque psoriasis; Psoriasis vulgaris; Quality of life; TNF-α-inhibitor

Mesh:

Substances:

Year:  2015        PMID: 26349681     DOI: 10.1007/s00105-015-3680-3

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  5 in total

Review 1.  Biologic response modifiers and pediatric psoriasis.

Authors:  Fernanda Bellodi Schmidt; Kara N Shah
Journal:  Pediatr Dermatol       Date:  2015-02-26       Impact factor: 1.588

2.  A comparative study of pediatric onset psoriasis with adult onset psoriasis.

Authors:  S P Raychaudhuri; J Gross
Journal:  Pediatr Dermatol       Date:  2000 May-Jun       Impact factor: 1.588

3.  Long-term etanercept in pediatric patients with plaque psoriasis.

Authors:  Amy S Paller; Elaine C Siegfried; Lawrence F Eichenfield; David Pariser; Richard G Langley; Kara Creamer; Greg Kricorian
Journal:  J Am Acad Dermatol       Date:  2010-06-03       Impact factor: 11.527

4.  Etanercept for psoriasis in the pediatric population: experience in nine patients.

Authors:  Aimee C Hawrot; Denise W Metry; Amy J Theos; Moise L Levy
Journal:  Pediatr Dermatol       Date:  2006 Jan-Feb       Impact factor: 1.588

5.  Etanercept treatment for children and adolescents with plaque psoriasis.

Authors:  Amy S Paller; Elaine C Siegfried; Richard G Langley; Alice B Gottlieb; David Pariser; Ian Landells; Adelaide A Hebert; Lawrence F Eichenfield; Vaishali Patel; Kara Creamer; Angelika Jahreis
Journal:  N Engl J Med       Date:  2008-01-17       Impact factor: 91.245

  5 in total

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