| Literature DB >> 26348535 |
Zheng-Xi Hu1,2, Yi-Ming Shi1, Wei-Guang Wang1, Xiao-Nian Li1, Xue Du1, Miao Liu1, Yan Li1, Yong-Bo Xue2, Yong-Hui Zhang2, Jian-Xin Pu1, Han-Dong Sun1.
Abstract
Six new lanostane-related triterpenoids, kadcoccinones A-F (1-6), were isolated from Kadsura coccinea. Compound 3 possesses a novel 6/6/9-fused carbocyclic core containing a rare oxabicyclo[4.3.1]decane system. Compounds 4 and 5 are isomers representing the first example of the 18(13 → 12)-abeo-26-norlanostane triterpenoid. The absolute configurations of 1 and 4-6 were defined by X-ray diffraction and experimental ECD spectra, and that of 3 was elucidated by quantum chemical calculations. The plausible biogenetic pathway of 1-6 is postulated.Entities:
Mesh：
Substances：
Year: 2015 PMID： 26348535 DOI： 10.1021/acs.orglett.5b02360
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005