Literature DB >> 26348011

Delayed Hyponatremia Is the Most Common Cause of 30-Day Unplanned Readmission After Transsphenoidal Surgery for Pituitary Tumors.

Michael A Bohl1, Shah Ahmad, Heidi Jahnke, Deborah Shepherd, Laura Knecht, William L White, Andrew S Little.   

Abstract

BACKGROUND: Unplanned readmission after surgical procedures is an important quality metric. Yet, readmission rates and causes have not been evaluated for patients after transsphenoidal surgery for pituitary tumors.
OBJECTIVE: To analyze unplanned 30-day readmissions at a pituitary center and to encourage the development of effective clinical pathways to prevent readmission.
METHODS: A retrospective review of adult patients who underwent transsphenoidal surgery for pituitary lesions at Barrow Neurological Institute (January 2011-March 2014) was performed to identify causes of unplanned readmission within 30 days of surgery. Patient demographics, tumor details, surgical complications, and endocrine function were documented.
RESULTS: Of 303 patients who had transsphenoidal surgery, 27 (8.9%) were readmitted within 30 days. Most of the 27 (15 [55.6%]) had delayed hyponatremia. Other causes were diabetes insipidus (4 [14.8%]), adrenal insufficiency (2 [7.4%]), and cerebrospinal fluid leak, epistaxis, cardiac arrhythmia, pneumonia, urinary tract infection, and hypoglycemia (1 each [3.7%]). Outpatient sodium screening was performed as needed. In cases of hyponatremia, the mean postoperative day of readmission was day 8 (range, 6-12 days) and the mean serum sodium was 119 mmol/L (range, 111-129 mmol/L). Numerous patient and surgical factors were examined, and no specific predictors of readmission were identified. We developed an outpatient care pathway for managing hyponatremia with the goal of improving readmission rates.
CONCLUSION: This study establishes a quality benchmark for readmission rates after transsphenoidal surgery for pituitary lesions and identifies delayed hyponatremia as the primary cause. Implementation of an outpatient care pathway for managing hyponatremia may improve readmission rates.

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Mesh:

Year:  2016        PMID: 26348011     DOI: 10.1227/NEU.0000000000001003

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  27 in total

1.  National trends in hospital readmission following transsphenoidal surgery for pituitary lesions.

Authors:  Kelly A Shaftel; Tyler S Cole; Andrew S Little
Journal:  Pituitary       Date:  2020-04       Impact factor: 4.107

2.  Diabetes insipidus and syndrome of inappropriate antidiuresis (SIADH) after pituitary surgery: incidence and risk factors.

Authors:  Elena L Sorba; Victor E Staartjes; Stefanos Voglis; Lazar Tosic; Giovanna Brandi; Oliver Tschopp; Carlo Serra; Luca Regli
Journal:  Neurosurg Rev       Date:  2020-06-24       Impact factor: 3.042

3.  Postoperative Diabetes Insipidus and Hyponatremia in Children after Transsphenoidal Surgery for Adrenocorticotropin Hormone and Growth Hormone Secreting Adenomas.

Authors:  Carolina Saldarriaga; Charlampos Lyssikatos; Elena Belyavskaya; Margaret Keil; Prashant Chittiboina; Ninet Sinaii; Constantine A Stratakis; Maya Lodish
Journal:  J Pediatr       Date:  2018-02-01       Impact factor: 4.406

Review 4.  Multidisciplinary management of acromegaly: A consensus.

Authors:  Andrea Giustina; Garni Barkhoudarian; Albert Beckers; Anat Ben-Shlomo; Nienke Biermasz; Beverly Biller; Cesar Boguszewski; Marek Bolanowski; Jens Bollerslev; Vivien Bonert; Marcello D Bronstein; Michael Buchfelder; Felipe Casanueva; Philippe Chanson; David Clemmons; Maria Fleseriu; Anna Maria Formenti; Pamela Freda; Monica Gadelha; Eliza Geer; Mark Gurnell; Anthony P Heaney; Ken K Y Ho; Adriana G Ioachimescu; Steven Lamberts; Edward Laws; Marco Losa; Pietro Maffei; Adam Mamelak; Moises Mercado; Mark Molitch; Pietro Mortini; Alberto M Pereira; Stephan Petersenn; Kalmon Post; Manuel Puig-Domingo; Roberto Salvatori; Susan L Samson; Ilan Shimon; Christian Strasburger; Brooke Swearingen; Peter Trainer; Mary L Vance; John Wass; Margaret E Wierman; Kevin C J Yuen; Maria Chiara Zatelli; Shlomo Melmed
Journal:  Rev Endocr Metab Disord       Date:  2020-09-10       Impact factor: 6.514

5.  Smoking and Obesity are Risk Factors for Thirty-Day Readmissions Following Skull Base Surgery.

Authors:  Milan Makwana; Peter N Taylor; Benjamin T Stew; Geoffrey Shone; Caroline Hayhurst
Journal:  J Neurol Surg B Skull Base       Date:  2019-04-02

6.  Diabetes Insipidus following Endoscopic Transsphenoidal Surgery for Pituitary Adenoma.

Authors:  Abdulrazag M Ajlan; Sarah Bin Abdulqader; Achal S Achrol; Yousef Aljamaan; Abdullah H Feroze; Laurence Katznelson; Griffith R Harsh
Journal:  J Neurol Surg B Skull Base       Date:  2017-08-03

7.  Strategies to reduce readmissions for hyponatremia after transsphenoidal surgery for pituitary adenomas.

Authors:  Kelsi E Deaver; Colin P Catel; Kevin O Lillehei; Margaret E Wierman; Janice M Kerr
Journal:  Endocrine       Date:  2018-06-30       Impact factor: 3.633

8.  Hypothalamus-Pituitary Dysfunction as an Independent Risk Factor for Postoperative Central Nervous System Infections in Patients With Sellar Region Tumors.

Authors:  Junxian Wen; Rui Yin; Yihao Chen; Jianbo Chang; Baitao Ma; Wei Zuo; Xiao Zhang; Xiaojun Ma; Ming Feng; Renzhi Wang; Wenbin Ma; Junji Wei
Journal:  Front Endocrinol (Lausanne)       Date:  2021-04-30       Impact factor: 5.555

9.  Diaphragma sellae sinking can predict the onset of hyponatremia after transsphenoidal surgery for pituitary adenomas.

Authors:  Kunzhe Lin; Jun Li; Lingling Lu; Shangming Zhang; Shuwen Mu; Zhijie Pei; Cheng Wang; Jingying Lin; Liang Xue; Liangfeng Wei; Lin Zhao; Shousen Wang
Journal:  J Endocrinol Invest       Date:  2021-06-14       Impact factor: 4.256

10.  Tolvaptan in the Management of Acute Euvolemic Hyponatremia After Transsphenoidal Surgery: A Retrospective Single-Center Analysis.

Authors:  Rita Indirli; Júlia Ferreira de Carvalho; Arianna Cremaschi; Beatrice Mantovani; Elisa Sala; Andreea Liliana Serban; Marco Locatelli; Giulio Bertani; Giulia Carosi; Giorgio Fiore; Leonardo Tariciotti; Maura Arosio; Giovanna Mantovani; Emanuele Ferrante
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-24       Impact factor: 5.555

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