| Literature DB >> 26347504 |
B Anne Neville1, Christophe d'Enfert2, Marie-Elisabeth Bougnoux3.
Abstract
Candida albicans is a polymorphic yeast species that often forms part of the commensal gastrointestinal mycobiota of healthy humans. It is also an important opportunistic pathogen. A tripartite interaction involving C. albicans, the resident microbiota and host immunity maintains C. albicans in its commensal form. The influence of each of these factors on C. albicans carriage is considered herein, with particular focus on the mycobiota and the approaches used to study it, models of gastrointestinal colonization by C. albicans, the C. albicans genes and phenotypes that are necessary for commensalism and the host factors that influence C. albicans carriage. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.Entities:
Keywords: Candida albicans; animal models; commensalism; gastrointestinal tract; immunity; microbiota; mycobiota
Mesh:
Year: 2015 PMID: 26347504 DOI: 10.1093/femsyr/fov081
Source DB: PubMed Journal: FEMS Yeast Res ISSN: 1567-1356 Impact factor: 2.796