OBJECTIVE: To assess whether dual-frequency ultrasound can improve the treatment results of injection lipolysis (IL). DESIGN: Randomized, single-center pilot study. All subjects were treated with a contralateral control: one side of the body received the treatment with IL, whereas the symmetrical contralateral side received the combination of IL with dual-frequency ultrasound in a special form (LDM). Injections were provided subcutaneously in the depth of 8 to 12mm with a distance of nearly 15mm between the single injections. All subjects were treated with LDM once, 1 to 3 hours before the injection and twice per week after the injection. SETTING: Kosmed Clinic, Kiel, Germany. PARTICIPANTS: Seven female healthy subjects with local body contouring problems in femoral or upper arm regions. MEASUREMENTS: Circumference was measured before and 6 to 8 weeks after treatment. Pain, hematoma, itching, burning sensation, redness, swelling, and pressure sensation were evaluated before the first treatment and 6 to 8 weeks for both contralateral sides. RESULTS: Application of LDM in combination with IL improved the volume reduction compared to pure IL by 65.6 percent. The difference between IL and IL+LDM treated sides showed very high significance (p≤0.0001). Significant differences between IL and IL+LDM treated areas were found also in pain (p≤0.01). No statistical difference was found in all other subjective parameters. CONCLUSION: Application of LDM significantly increases the treatment success after IL and the acceptance of IL procedures by patients.
RCT Entities:
OBJECTIVE: To assess whether dual-frequency ultrasound can improve the treatment results of injection lipolysis (IL). DESIGN: Randomized, single-center pilot study. All subjects were treated with a contralateral control: one side of the body received the treatment with IL, whereas the symmetrical contralateral side received the combination of IL with dual-frequency ultrasound in a special form (LDM). Injections were provided subcutaneously in the depth of 8 to 12mm with a distance of nearly 15mm between the single injections. All subjects were treated with LDM once, 1 to 3 hours before the injection and twice per week after the injection. SETTING: Kosmed Clinic, Kiel, Germany. PARTICIPANTS: Seven female healthy subjects with local body contouring problems in femoral or upper arm regions. MEASUREMENTS: Circumference was measured before and 6 to 8 weeks after treatment. Pain, hematoma, itching, burning sensation, redness, swelling, and pressure sensation were evaluated before the first treatment and 6 to 8 weeks for both contralateral sides. RESULTS: Application of LDM in combination with IL improved the volume reduction compared to pure IL by 65.6 percent. The difference between IL and IL+LDM treated sides showed very high significance (p≤0.0001). Significant differences between IL and IL+LDM treated areas were found also in pain (p≤0.01). No statistical difference was found in all other subjective parameters. CONCLUSION: Application of LDM significantly increases the treatment success after IL and the acceptance of IL procedures by patients.
Authors: Judith M Watson; Arthur R Kang'ombe; Marta O Soares; Ling-Hsiang Chuang; Gill Worthy; J Martin Bland; Cynthia Iglesias; Nicky Cullum; David Torgerson; E Andrea Nelson Journal: BMJ Date: 2011-03-08