Literature DB >> 26345483

The effect of knee joint loading and immobilization on the femoral cartilage thickness in paraplegics.

B Yilmaz1, Y Demir1, E Özyörük1, S Kesikburun1, Ü Güzelküçük1.   

Abstract

BACKGROUND: Femoral cartilage thickness has been used as an indicator for immobilization and unloading in patients with spinal cord injury (SCI). However, conflicting results have been reported on this subject.
OBJECTIVES: (i) To determine femoral cartilage thickness alterations after prolonged immobilization, (ii) to demonstrate the effect of the daily standing or ambulation time on the cartilage and (iii) to analyze the predictors of the femoral cartilage in patients with SCI.
METHODS: A total of 50 patients with SCI and 50 healthy age and sex-matched volunteers were enrolled in the study. A physician scanned both knees of all participants and measurements were taken at three locations: trochlear notch, midpoints of the medial and lateral condyle.
RESULTS: The trochlear notch, medial and lateral condyle femoral cartilage thickness of both sides were significantly thicker in the control group (P<0.05). Patients with <1 h daily standing/walking time had higher thickness measurements in all sub parameters than patients with >1 h daily standing/walking time (P<0.05). Daily standing/walking time and the Walking index for SCI score were statistically significant predictors for cartilage thickness.
CONCLUSION: SCI patients had thinner knee cartilage compared with healthy individuals in ultrasonographic assessment. More than 1 h daily standing/walking time may have a negative effect on the femoral cartilage thickness. Thus, ultrasonographic evaluation of the femoral cartilage should be considered in clinical practice to detect early cartilage thinning in patients with SCI.

Entities:  

Mesh:

Year:  2015        PMID: 26345483     DOI: 10.1038/sc.2015.151

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  15 in total

1.  Walking index for spinal cord injury (WISCI II): scale revision.

Authors:  P L Dittuno; J F Ditunno; J F Dittuno
Journal:  Spinal Cord       Date:  2001-12       Impact factor: 2.772

2.  International standards for neurological classification of spinal cord injury (revised 2011).

Authors:  Steven C Kirshblum; Stephen P Burns; Fin Biering-Sorensen; William Donovan; Daniel E Graves; Amitabh Jha; Mark Johansen; Linda Jones; Andrei Krassioukov; M J Mulcahey; Mary Schmidt-Read; William Waring
Journal:  J Spinal Cord Med       Date:  2011-11       Impact factor: 1.985

3.  Unweighting accelerates tidemark advancement in articular cartilage at the knee joint of rats.

Authors:  K M O'Connor
Journal:  J Bone Miner Res       Date:  1997-04       Impact factor: 6.741

4.  The intra-articular effects of immobilization on the human knee.

Authors:  W F Enneking; M Horowitz
Journal:  J Bone Joint Surg Am       Date:  1972-07       Impact factor: 5.284

5.  Remobilization does not fully restore immobilization induced articular cartilage atrophy.

Authors:  J Haapala; J P Arokoski; M M Hyttinen; M Lammi; M Tammi; V Kovanen; H J Helminen; I Kiviranta
Journal:  Clin Orthop Relat Res       Date:  1999-05       Impact factor: 4.176

6.  Comparison of Intact Knee Cartilage Thickness in Patients with Traumatic Lower Extremity Amputation and Nonimpaired Individuals.

Authors:  Serdar Kesikburun; Özlem Köroğlu; Evren Yaşar; Ümüt Güzelküçük; Kamil Yazcoğlu; Arif Kenan Tan
Journal:  Am J Phys Med Rehabil       Date:  2015-08       Impact factor: 2.159

7.  Weight bearing controls glycosaminoglycan concentration and articular cartilage thickness in the knee joints of young beagle dogs.

Authors:  I Kiviranta; J Jurvelin; M Tammi; A M Säämänen; H J Helminen
Journal:  Arthritis Rheum       Date:  1987-07

8.  Knee cartilage of spinal cord-injured patients displays progressive thinning in the absence of normal joint loading and movement.

Authors:  B Vanwanseele; F Eckstein; H Knecht; E Stüssi; A Spaepen
Journal:  Arthritis Rheum       Date:  2002-08

9.  Longitudinal analysis of cartilage atrophy in the knees of patients with spinal cord injury.

Authors:  B Vanwanseele; F Eckstein; H Knecht; A Spaepen; E Stüssi
Journal:  Arthritis Rheum       Date:  2003-12

10.  Ultrasonographic assessment of diurnal variation in the femoral condylar cartilage thickness in healthy young adults.

Authors:  Gamze Kilic; Erkan Kilic; Ozgur Akgul; Salih Ozgocmen
Journal:  Am J Phys Med Rehabil       Date:  2015-04       Impact factor: 2.159

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  1 in total

1.  The influence of a sustained 10-day hypoxic bed rest on cartilage biomarkers and subchondral bone in females: The FemHab study.

Authors:  Adam C McDonnell; Ola Eiken; Igor B Mekjavic; Nik Žlak; Matej Drobnič
Journal:  Physiol Rep       Date:  2020-04
  1 in total

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