Literature DB >> 26344462

Sudden cardiac death among general population and sport related population in forensic experience.

Nina Chappex1, Jürg Schlaepfer2, Florence Fellmann3, Zahurul A Bhuiyan3, Matthias Wilhelm4, Katarzyna Michaud5.   

Abstract

PURPOSE: The goal of the study was to assess the causes and analyze the cases of sudden cardiac death (SCD) victims referred to the department of forensic medicine in Lausanne, with a particular focus on sports-related fatalities including also leisure sporting activities. To date, no such published assessment has been done nor for Switzerland nor for the central Europe.
METHODS: This is a retrospective study based on autopsy records of SCD victims, from 10 to 50 years of age, performed at the University Centre of Legal Medicine in Lausanne from 1995 to 2010. The study population was divided into two groups: sport-related (SR) and not sport-related (NSR) SCDs.
RESULTS: During the study period, 188 cases of SCD were recorded: 166 (88%) were NSR and 22 (12%) SR. The mean age of the 188 victims was 37.3 ± 10.1 years, with the majority of the cases being male (79%). A cause of death was established in 84%, and the pathology responsible for death varied according to the age of the victims. In the NSR group, the mean age was 38.2 ± 9.2 years and there was 82% of male. Coronary artery disease (CAD) was the main diagnosis in the victims aged 30-50 years. The majority of morphologically normal hearts were observed in the 15-29 year age range. There was no case in the 10-14 year age range. In the SR group, 91% of victims died during leisure sporting activities. In this group the mean age was 30.5 ± 13.5 years, with the majority being male (82%). The main cause of death was CAD, with 6 cases (27%) and a mean age of 40.8 ± 5.5 years. The youngest victim with CAD was 33 years old. A morphologically normal heart was observed in 5 cases (23%), with a mean age of 24.4 ± 14.9 years. The most frequently implicated sporting activities were hiking (26%) and swimming (17%).
CONCLUSION: In this study, CAD was the most common cause of death in both groups. Although this pathology most often affects adults over 35 years of age, there were also some victims under 35 years of age in both groups. SCDs during sport are mostly related to leisure sporting activities, for which preventive measures are not yet usually established. This study highlights also the need to inform both athletes and non athletes of the cardiovascular risks during sport activities and the role of a forensic autopsy and registries involving forensic pathologists for SR SCD.
Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Entities:  

Keywords:  Coronary artery disease in the young; Registries; Sport-related deaths; Sudden cardiac death

Mesh:

Year:  2015        PMID: 26344462     DOI: 10.1016/j.jflm.2015.07.004

Source DB:  PubMed          Journal:  J Forensic Leg Med        ISSN: 1752-928X            Impact factor:   1.614


  11 in total

1.  Sudden death due to catecholaminergic polymorphic ventricular tachycardia following negative stress-test outcome: genetics and clinical implications.

Authors:  Cristian D'Ovidio; Aldo Carnevale; Vincenzo M Grassi; Enrica Rosato; Bernat Del Olmo; Monica Coll; Oscar Campuzano; Anna Iglesias; Ramon Brugada; Antonio Oliva
Journal:  Forensic Sci Med Pathol       Date:  2017-04-13       Impact factor: 2.007

Review 2.  Medico-legal perspectives on sudden cardiac death in young athletes.

Authors:  Antonio Oliva; Vincenzo M Grassi; Oscar Campuzano; Maria Brion; Vincenzo Arena; Sara Partemi; Monica Coll; Vincenzo L Pascali; Josep Brugada; Angel Carracedo; Ramon Brugada
Journal:  Int J Legal Med       Date:  2016-09-21       Impact factor: 2.686

3.  Post-mortem genetic investigation in sudden cardiac death victims: complete exon sequencing of forty genes using next-generation sequencing.

Authors:  Jennifer Fadoni; Agostinho Santos; Laura Cainé
Journal:  Int J Legal Med       Date:  2022-01-05       Impact factor: 2.791

4.  Decreased mRNA levels of cardiac Cx43 and ZO1 in sudden cardiac death related to coronary atherosclerosis: a pilot study.

Authors:  Ye Xue; Rui Zhao; Si-Hao Du; Dong Zhao; Dong-Ri Li; Jing-Tao Xu; Xiao-Li Xie; Qi Wang
Journal:  Int J Legal Med       Date:  2016-03-14       Impact factor: 2.686

5.  2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families.

Authors:  Martin K Stiles; Arthur A M Wilde; Dominic J Abrams; Michael J Ackerman; Christine M Albert; Elijah R Behr; Sumeet S Chugh; Martina C Cornel; Karen Gardner; Jodie Ingles; Cynthia A James; Jyh-Ming Jimmy Juang; Stefan Kääb; Elizabeth S Kaufman; Andrew D Krahn; Steven A Lubitz; Heather MacLeod; Carlos A Morillo; Koonlawee Nademanee; Vincent Probst; Elizabeth V Saarel; Luciana Sacilotto; Christopher Semsarian; Mary N Sheppard; Wataru Shimizu; Jonathan R Skinner; Jacob Tfelt-Hansen; Dao Wu Wang
Journal:  Heart Rhythm       Date:  2020-10-19       Impact factor: 6.343

6.  Sudden death during struggle in the setting of heterozygosity for a mutation in calsequesterin 2.

Authors:  Ashwyn Rajagopalan; Michael S Pollanen
Journal:  Forensic Sci Med Pathol       Date:  2015-12-15       Impact factor: 2.007

7.  2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families.

Authors:  Martin K Stiles; Arthur A M Wilde; Dominic J Abrams; Michael J Ackerman; Christine M Albert; Elijah R Behr; Sumeet S Chugh; Martina C Cornel; Karen Gardner; Jodie Ingles; Cynthia A James; Jyh-Ming Jimmy Juang; Stefan Kääb; Elizabeth S Kaufman; Andrew D Krahn; Steven A Lubitz; Heather MacLeod; Carlos A Morillo; Koonlawee Nademanee; Vincent Probst; Elizabeth V Saarel; Luciana Sacilotto; Christopher Semsarian; Mary N Sheppard; Wataru Shimizu; Jonathan R Skinner; Jacob Tfelt-Hansen; Dao Wu Wang
Journal:  J Arrhythm       Date:  2021-04-08

8.  Sports-related sudden cardiac deaths in the young population of Switzerland.

Authors:  Babken Asatryan; Cristina Vital; Christoph Kellerhals; Argelia Medeiros-Domingo; Christoph Gräni; Lukas D Trachsel; Christian M Schmied; Ardan M Saguner; Prisca Eser; David Herzig; Stephan Bolliger; Katarzyna Michaud; Matthias Wilhelm
Journal:  PLoS One       Date:  2017-03-28       Impact factor: 3.240

9.  Sports-related sudden cardiac death due to myocardial diseases on a population from 1-35 years: a multicentre forensic study in Spain.

Authors:  Benito Morentin; M Paz Suárez-Mier; Ana Monzó; Pilar Molina; Joaquín S Lucena
Journal:  Forensic Sci Res       Date:  2019-08-19

10.  Death in Community Australian Football: A Ten Year National Insurance Claims Report.

Authors:  Lauren V Fortington; Caroline F Finch
Journal:  PLoS One       Date:  2016-07-28       Impact factor: 3.240

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