Amy T Peters1, Stewart A Shankman1, Thilo Deckersbach2, Amy E West3. 1. University of Illinois at Chicago, Departments of Psychiatry and Psychology, United States. 2. Massachusetts General Hospital, Department of Psychiatry, United States; Harvard Medical School, Department of Psychiatry, United States. 3. University of Illinois at Chicago, Departments of Psychiatry and Psychology, United States. Electronic address: Awest@psych.uic.edu.
Abstract
BACKGROUND: The aim of this study is to assess predictors of first-episode major depression in a community-based sample of adults with and without sub-threshold depression. METHOD: Data were from Waves 1 and 2 of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). Participants meeting criteria for a sub-threshold depressive episode (sMDE; n=3901) reported lifetime depressed mood/loss of interest lasting at least two weeks and at least two of the seven other DSM-IV symptoms of MDD. Predictors of MDE 3 years later were compared in those with and without (n=31022) sMDE. RESULTS: Being female, history of alcohol or substance use, and child abuse increased the odds of developing MDD to a greater degree in individuals without sMDE relative to those with sMDE. Among those with sMDE and additional risk factors (low education, substance use), younger age was associated with marginally increased risk of MDD. CONCLUSION: Several demographic risk factors may help identify individuals at risk for developing MDD in individuals who have not experienced an sMDE who may be candidates for early intervention. Future work should assess whether preventative interventions targeting substance/alcohol use and child abuse could reduce the risk of depression.
BACKGROUND: The aim of this study is to assess predictors of first-episode major depression in a community-based sample of adults with and without sub-threshold depression. METHOD: Data were from Waves 1 and 2 of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). Participants meeting criteria for a sub-threshold depressive episode (sMDE; n=3901) reported lifetime depressed mood/loss of interest lasting at least two weeks and at least two of the seven other DSM-IV symptoms of MDD. Predictors of MDE 3 years later were compared in those with and without (n=31022) sMDE. RESULTS: Being female, history of alcohol or substance use, and child abuse increased the odds of developing MDD to a greater degree in individuals without sMDE relative to those with sMDE. Among those with sMDE and additional risk factors (low education, substance use), younger age was associated with marginally increased risk of MDD. CONCLUSION: Several demographic risk factors may help identify individuals at risk for developing MDD in individuals who have not experienced an sMDE who may be candidates for early intervention. Future work should assess whether preventative interventions targeting substance/alcohol use and child abuse could reduce the risk of depression.
Authors: Camila Maria Severi Martins; Cristiane Von Werne Baes; Sandra Marcia de Carvalho Tofoli; Mario Francisco Juruena Journal: J Nerv Ment Dis Date: 2014-11 Impact factor: 2.254
Authors: Lisa A Uebelacker; Beth A Marootian; Paul A Pirraglia; Jennifer Primack; Patrick M Tigue; Ryan Haggarty; Lavinia Velazquez; Jennifer J Bowdoin; Zornitsa Kalibatseva; Ivan W Miller Journal: Community Ment Health J Date: 2011-01-26
Authors: Gabriel Abotsie; Viktoria Cestaro; Brioney Gee; Jamie Murdoch; Thando Katangwe; Richard Meiser-Stedman; Lee Shepstone; David Turner; Susie Tulk; Sharon Jarrett; Jon Wilson; Tim Clarke; Bonnie Teague; Paul Wilkinson Journal: Pilot Feasibility Stud Date: 2020-12-10