Literature DB >> 26341691

[Treatment reality of internal carotid artery stenosis in Germany : requirement and reality in international comparison and in light of the current S3 guidelines].

J Eyding1,2, M Kitzrow3,4, C Krogias5,4, G Reimann6,4, R Weber7,4, C Weimar8,4, D Bartig9,4.   

Abstract

BACKGROUND: Severe atherosclerotic extracranial carotid artery stenosis accounts for 5-10 % of all ischemic strokes. Currently, therapeutic recommendations are undergoing changes, particularly regarding the treatment of asymptomatic stenosis. Consolidated knowledge on the indications, nationwide distribution and numbers of cases are not available. Moreover, the impact and grade of implementation of the recently published national S3 guidelines on the reality of medical treatment remain unclear.
METHODS: Analysis of administrative hospital data involving the diagnosis-related groups (DRG) statistics and structured quality reports for 2010 and 2013 to evaluate the procedural therapy trends concerning operative and interventional approaches for symptomatic and asymptomatic carotid artery stenoses.
RESULTS: In Germany approximately 37,000 carotid endarterectomies (CEA) and approximately 5,000 carotid angioplasties with stenting (CAS) are carried out per year. Approximately 94 % of CEA and 62 % of CAS are performed in centers with more than 25 procedures per year. Only 33 % of CEA and 39 % of CAS are related to symptomatic stenosis.
CONCLUSION: Mathematically, an undertreatment of symptomatic and an overtreatment of asymptomatic carotid artery stenoses become apparent. Efforts should be made to achieve inpatient medical treatment conforming to the national S3 guidelines, in particular to adequately reduce the risk of stroke recurrence in patients with atherosclerotic symptomatic carotid artery stenosis.

Entities:  

Keywords:  Angioplasty; Asymptomatic; Carotid artery stenosis; Endarterectomy; Symptomatic

Mesh:

Year:  2015        PMID: 26341691     DOI: 10.1007/s00115-015-4419-1

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  29 in total

Review 1.  [Revision of DEGUM ultrasound criteria for grading internal carotid artery stenoses and transfer to NASCET measurement].

Authors:  C Arning; B Widder; G M von Reutern; H Stiegler; M Görtler
Journal:  Ultraschall Med       Date:  2010-04-22       Impact factor: 6.548

2.  2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery.

Authors:  Thomas G Brott; Jonathan L Halperin; Suhny Abbara; J Michael Bacharach; John D Barr; Ruth L Bush; Christopher U Cates; Mark A Creager; Susan B Fowler; Gary Friday; Vicki S Hertzberg; E Bruce McIff; Wesley S Moore; Peter D Panagos; Thomas S Riles; Robert H Rosenwasser; Allen J Taylor
Journal:  Circulation       Date:  2011-01-31       Impact factor: 29.690

3.  Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)

Authors: 
Journal:  Lancet       Date:  1998-05-09       Impact factor: 79.321

4.  Treating individuals 3: from subgroups to individuals: general principles and the example of carotid endarterectomy.

Authors:  Peter M Rothwell; Ziyah Mehta; Sally C Howard; Sergei A Gutnikov; Charles P Warlow
Journal:  Lancet       Date:  2005 Jan 15-21       Impact factor: 79.321

5.  Distribution and outcome of symptomatic stenoses and occlusions in patients with acute cerebral ischemia.

Authors:  Christian Weimar; Michael Goertler; Lutz Harms; Hans-Christoph Diener
Journal:  Arch Neurol       Date:  2006-09

6.  Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis.

Authors:  J David Spence; Victoria Coates; Hector Li; Arturo Tamayo; Claudio Muñoz; Daniel G Hackam; Maria DiCicco; Janine DesRoches; Chrysi Bogiatzi; Jonathan Klein; Joaquim Madrenas; Robert A Hegele
Journal:  Arch Neurol       Date:  2009-12-14

7.  Outcome in patients with asymptomatic neck bruits.

Authors:  B R Chambers; J W Norris
Journal:  N Engl J Med       Date:  1986-10-02       Impact factor: 91.245

8.  Low risk of ipsilateral stroke in patients with asymptomatic carotid stenosis on best medical treatment: a prospective, population-based study.

Authors:  Lars Marquardt; Olivia C Geraghty; Ziyah Mehta; Peter M Rothwell
Journal:  Stroke       Date:  2009-11-19       Impact factor: 7.914

9.  Asymptomatic carotid artery stenosis and the risk of ischemic stroke according to subtype in patients with clinical manifest arterial disease.

Authors:  Anne G den Hartog; Sefanja Achterberg; Frans L Moll; L Jaap Kappelle; Frank L J Visseren; Yolanda van der Graaf; Ale Algra; Gert Jan de Borst
Journal:  Stroke       Date:  2013-02-12       Impact factor: 7.914

Review 10.  Prevalence of asymptomatic carotid artery stenosis according to age and sex: systematic review and metaregression analysis.

Authors:  Marjolein de Weerd; Jacoba P Greving; Anne W F de Jong; Erik Buskens; Michiel L Bots
Journal:  Stroke       Date:  2009-02-26       Impact factor: 7.914

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