Katharine L Warburton1, Andrea Bauer2, Mahbub M U Chowdhury3, Susan Cooper4, Beata Kręcisz5, Dorota Chomiczewska-Skóra5, Marta Kieć-Świerczyńska5, Francesca L Filon6, Vera Mahler7, Javier Sánchez-Pérez8, Axel Schnuch9, Wolfgang Uter10, Mark Wilkinson1. 1. Department of Dermatology, The Leeds Teaching Hospitals NHS Trust, Leeds LS7 4SA, UK. 2. Department of Dermatology, University Allergy Centre, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden D-01307, Germany. 3. Welsh Institute of Dermatology, Cardiff CF14 4XN, UK. 4. Department of Dermatology, Churchill Hospital, Oxford OX3 7LJ, UK. 5. Nofer Institute of Occupational Medicine, Lodz 91-348, Poland. 6. Department of Public Health, Occupational Medicine, University of Trieste, IT-34129 Trieste, Italy. 7. Allergy Unit, Department of Dermatology, University Hospital Erlangen, 91054 Erlangen, Germany. 8. Department of Dermatology, Hospital Universitario de la Princesa, 28006 Madrid, Spain. 9. Information Network of Departments of Dermatology, University Medicine Göttingen, 37075 Göttingen, Germany. 10. Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen/Nurnberg, 91054 Erlangen, Germany.
Abstract
BACKGROUND: Allergic contact dermatitis caused by rubber allergens is common, and causes significant patient morbidity. Contemporary data are important to allow appropriate preventive measures and identification of contact allergy trends. OBJECTIVES: To describe the pattern of patch test reactivity to rubber allergens, including those in the European baseline series. METHODS: Data collected by the European Surveillance System on Contact Allergies (ESSCA) network between 2009 and 2012 from 12 European countries were analysed. RESULTS: Contact allergy to thiuram mix declined over the studied time period, with an overall prevalence of 1.87%. The prevalence of allergy to carba mix was 2.29%, and was significantly increasing. Prevalence rates of sensitization to other rubber allergens were largely unchanged. Statistical analysis with the MOAHLFA index confirmed the strong links between rubber allergy and occupational hand dermatitis. CONCLUSIONS: Changing patterns of allergy to rubber additives have been identified. Inclusion of carba mix in the European baseline series may be appropriate.
BACKGROUND: Allergic contact dermatitis caused by rubber allergens is common, and causes significant patient morbidity. Contemporary data are important to allow appropriate preventive measures and identification of contact allergy trends. OBJECTIVES: To describe the pattern of patch test reactivity to rubber allergens, including those in the European baseline series. METHODS: Data collected by the European Surveillance System on Contact Allergies (ESSCA) network between 2009 and 2012 from 12 European countries were analysed. RESULTS: Contact allergy to thiuram mix declined over the studied time period, with an overall prevalence of 1.87%. The prevalence of allergy to carba mix was 2.29%, and was significantly increasing. Prevalence rates of sensitization to other rubber allergens were largely unchanged. Statistical analysis with the MOAHLFA index confirmed the strong links between rubber allergy and occupational hand dermatitis. CONCLUSIONS: Changing patterns of allergy to rubber additives have been identified. Inclusion of carba mix in the European baseline series may be appropriate.
Authors: Jart A F Oosterhaven; Wolfgang Uter; Werner Aberer; José C Armario-Hita; Barbara K Ballmer-Weber; Andrea Bauer; Magdalena Czarnecka-Operacz; Peter Elsner; Juan García-Gavín; Ana M Giménez-Arnau; Swen M John; Beata Kręcisz; Vera Mahler; Thomas Rustemeyer; Anna Sadowska-Przytocka; Javier Sánchez-Pérez; Dagmar Simon; Skaidra Valiukevičienė; Elke Weisshaar; Marie L A Schuttelaar Journal: Contact Dermatitis Date: 2019-01-14 Impact factor: 6.600
Authors: Anna Tagka; George I Lambrou; George K Matsopoulos; Despoina Fytili; Daphne Mirkopoulou; Alexandra Katsarou; Argyro Chatziioannou; Alexandros Stratigos Journal: Biomed Res Int Date: 2021-05-06 Impact factor: 3.411