Literature DB >> 26335822

The analysis of microRNAs miR-200C and miR-145 expression in colorectal cancer of different molecular subtypes.

Y A Shelygin1, V P Shubin, S A Frolov, S I Achkasov, O I Sushkov, A S Tsukanov, V N Kashnikov, N I Pospekhova.   

Abstract

The expression levels of microRNAs miR-200c and miR-145 in two groups of colorectal cancer differing by the presence/absence of epithelial-mesenchymal transition (EMF) were studied. In the EMF-positive cancer, the level of miR-145 is increased, whereas the level of miR-200c is reduced. The reverse situation is observed in the EMI-negative cancer. MiR-145 can serve as a marker of the mesenchymal subtype of cancer. Gene expression profiles and microRNAs allow prognostically unfavorable tumors of the mesenchymal subtype to be distinguished.

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Year:  2015        PMID： 26335822     DOI： 10.1134/S1607672915040122

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  14 in total

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Review 2.  MicroRNAs and epigenetics.

Authors:  Fumiaki Sato; Soken Tsuchiya; Stephen J Meltzer; Kazuharu Shimizu
Journal:  FEBS J       Date:  2011-03-30       Impact factor: 5.542

3.  Potential mRNA degradation targets of hsa-miR-200c, identified using informatics and qRT-PCR.

Authors:  Gregory J Hurteau; Simon D Spivack; Graham J Brock
Journal:  Cell Cycle       Date:  2006-09-01       Impact factor: 4.534

4.  Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells.

Authors:  Yujuan Shan; Lanwei Zhang; Yongping Bao; Baolong Li; Canxia He; Mingming Gao; Xue Feng; Weili Xu; Xiaohong Zhang; Shuran Wang
Journal:  J Nutr Biochem       Date:  2012-11-13       Impact factor: 6.048

5.  Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin.

Authors:  Gregory J Hurteau; J Andrew Carlson; Simon D Spivack; Graham J Brock
Journal:  Cancer Res       Date:  2007-09-01       Impact factor: 12.701

6.  A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis.

Authors:  Tobias Joyce; Daniela Cantarella; Claudio Isella; Enzo Medico; Alexander Pintzas
Journal:  Clin Exp Metastasis       Date:  2009-04-02       Impact factor: 5.150

Review 7.  Epithelial-mesenchymal transitions: insights from development.

Authors:  Jormay Lim; Jean Paul Thiery
Journal:  Development       Date:  2012-10       Impact factor: 6.868

8.  BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.

Authors:  Eleni Makrodouli; Eftychia Oikonomou; Michal Koc; Ladislav Andera; Takehiko Sasazuki; Senji Shirasawa; Alexander Pintzas
Journal:  Mol Cancer       Date:  2011-09-23       Impact factor: 27.401

9.  Epithelial-mesenchymal transition and somatic alteration in colorectal cancer with and without peritoneal carcinomatosis.

Authors:  Y A Shelygin; N I Pospekhova; V P Shubin; V N Kashnikov; S A Frolov; O I Sushkov; S I Achkasov; A S Tsukanov
Journal:  Biomed Res Int       Date:  2014-08-03       Impact factor: 3.411

10.  Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition.

Authors:  Paul Roepman; Andreas Schlicker; Josep Tabernero; Ian Majewski; Sun Tian; Victor Moreno; Mireille H Snel; Christine M Chresta; Robert Rosenberg; Ulrich Nitsche; Teresa Macarulla; Gabriel Capella; Ramon Salazar; George Orphanides; Lodewyk F A Wessels; Rene Bernards; Iris M Simon
Journal:  Int J Cancer       Date:  2013-09-13       Impact factor: 7.396
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