Literature DB >> 26335788

Chronic occupational N, N-dimethylformamide poisoning induced death: a case report.

Hui Zhang1, Quan Liu2, Yijie Duan3, Hongmei Dong4, Yiwu Zhou5.   

Abstract

N, N-dimethylformamide (DMF) is a toxic solvent that is widely used in many industries. Death directly attributed to DMF poisoning is rare. We report the case of a 40-year-old female who died of liver failure after occupational exposure to DMF poisoning over the course of 70 days, followed by 64 days treatment in hospital. Based on clinical procedures, autopsy findings, and environmental air quality assessment, the death in this case was confirmed to be the result of chronic DMF poisoning. This case gives further insight into occupational chronic poisoning-induced death, especially with negative toxicological analysis of rapid metabolism toxins poisoning.

Entities:  

Keywords:  Forensic pathology; Forensic toxicology; N, N-dimethylformamide (DMF); Negative toxicological analysis; Occupational disease

Mesh:

Substances:

Year:  2015        PMID: 26335788     DOI: 10.1007/s12024-015-9705-5

Source DB:  PubMed          Journal:  Forensic Sci Med Pathol        ISSN: 1547-769X            Impact factor:   2.007


  13 in total

1.  Metabolism studies of N,N-dimethylformamide. II. Studies in persons.

Authors:  G Kimmerle; A Eben
Journal:  Int Arch Arbeitsmed       Date:  1975

2.  [Death after exposure to dimethylformamide: a case report].

Authors:  Zhimin Tong; Jian Shi; Xu Zhu; Baoli Zhu
Journal:  Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi       Date:  2014-04

3.  Gas chromatographic method for the determination of N-acetyl-S-(N-methylcarbamoyl)cysteine, a metabolite of N,N-dimethylformamide and N-methylformamide, in human urine.

Authors:  J Mráz
Journal:  J Chromatogr       Date:  1988-10-14

4.  Letter: Toxicity of dimethylformamide.

Authors:  H P Potter
Journal:  Lancet       Date:  1974-11-02       Impact factor: 79.321

5.  Dimethylformamide-induced abdominal pain and liver injury.

Authors:  H P Potter
Journal:  Arch Environ Health       Date:  1973-11

6.  [Effect of N, N-dimethylformamide on oxidation or antioxidation status among occupational exposed workers].

Authors:  Juan Cheng; Qiang Liu; Bo Xu; Zhijun Wu; Meng Ye; Xiao Jiang; Chunmin Wang
Journal:  Zhonghua Yu Fang Yi Xue Za Zhi       Date:  2014-01

7.  Causal relationship between a case of severe hepatic dysfunction and low exposure concentrations of N,N-dimethylformamide in the synthetics industry.

Authors:  T Nomiyama; M Uehara; H Miyauchi; S Imamiya; S Tanaka; Y Seki
Journal:  Ind Health       Date:  2001-01       Impact factor: 2.179

8.  Metabolism and hepatotoxicity of N,N-dimethylformamide, N-hydroxymethyl-N-methylformamide, and N-methylformamide in the rat.

Authors:  M Van den Bulcke; M T Rosseel; P Wijnants; W Buylaert; F M Belpaire
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

9.  Occupational liver injury due to N,N-dimethylformamide in the synthetics industry.

Authors:  Maho Hamada; Masanori Abe; Yoshio Tokumoto; Teruki Miyake; Hidehiro Murakami; Yoichi Hiasa; Bunzo Matsuura; Kohei Sato; Morikazu Onji
Journal:  Intern Med       Date:  2009-09-15       Impact factor: 1.271

10.  High-performance liquid chromatographic determination of N-methylformamide and N-methyl-N-(hydroxymethyl)-formamide in human urine.

Authors:  G Santoni; P Bavazzano; A Perico; A Colzi; S Benassi; A Medica; R La Morgia; G Giuliano
Journal:  J Chromatogr       Date:  1992-10-23
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  3 in total

1.  N,N-dimethylformamide-induced acute hepatic failure: A case report and literature review.

Authors:  Yuanli Lei; Shasha Xiao; Shouquan Chen; Haiyan Zhang; Huiping Li; Yingru Lu
Journal:  Exp Ther Med       Date:  2017-09-27       Impact factor: 2.447

2.  A Case of Autoimmune Hepatitis after Occupational Exposure to N,N-Dimethylformamide.

Authors:  Boo Ok Jang; Gwang Hyeon Choi; Hee Yoon Jang; Soomin Ahn; Jae Kyun Choi; Siho Kim; Kyunghan Lee; Eun Sun Jang; Jin Wook Kim; Sook Hyang Jeong
Journal:  J Korean Med Sci       Date:  2020-07-20       Impact factor: 2.153

3.  The effects of dimethylformamide exposure on liver and kidney function in the elderly population: A cross-sectional study.

Authors:  Zhi-Yong Hu; Jie Chang; Fei-Fei Guo; Han-Yi Deng; Guo-Tao Pan; Bing-Yan Li; Zeng-Li Zhang
Journal:  Medicine (Baltimore)       Date:  2020-07-02       Impact factor: 1.817

  3 in total

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