| Literature DB >> 26335611 |
Andrea Bonetti, Sara Pellegrino, Priyadip Das1, Sivan Yuran1, Raffaella Bucci, Nicola Ferri2, Fiorella Meneghetti, Carlo Castellano, Meital Reches1, Maria Luisa Gelmi.
Abstract
The synthesis and the structural characterization of dipeptides composed of unnatural fluorine-substituted β(2,3)-diarylamino acid and L-alanine are reported. Depending on the stereochemistry of the β amino acid, these dipeptides are able to self-assemble into proteolytic stable nanotubes. These architectures were able to enter the cell and locate in the cytoplasmic/perinuclear region and represent interesting candidates for biomedical applications.Entities:
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Year: 2015 PMID: 26335611 DOI: 10.1021/acs.orglett.5b02132
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005