Literature DB >> 26335288

Comorbidities and factors associated with endoscopic surgical outcomes in adult laryngotracheal stenosis.

Pelin Kocdor1, Eric R Siegel2, James Y Suen1, Gresham Richter1, Ozlem E Tulunay-Ugur3.   

Abstract

This study which is a retrospective chart review aims to characterize the comorbidities associated with adult laryngotracheal stenosis and evaluate the relationship of these with stenosis grade, length, surgical interventions, and surgical intervals. Patients' demographics, medical and surgical comorbidities, grade of stenosis, quantity and degree of balloon dilations, dilation intervals, open airway procedures, and tracheotomy status were recorded from 2002 to 2012, at a tertiary voice and airway center. Surgical outcomes were evaluated in relation to patient comorbidities, stenosis quality, and surgical procedures. A total of 101 patients with laryngotracheal stenosis were examined with female patients comprising 71 % of the population. Seventeen patients (16.8 %) had idiopathic stenosis. Number of balloon dilations ranged from 0 to 24 (mean = 3.3). The average time between dilations was 38.4 weeks (range = 1.14-215.8 weeks). The patients with idiopathic stenosis were found to have a lower grade (p = 0.0066). Fifty-two patients (51.5 %) received a tracheotomy at one point during their management. The 14 patients (13.9 %) who remained tracheotomy dependent had a body mass index (BMI) of >30. No statistically significant correlation was found when the patients' age, BMI and comorbidites were compared with the grade of stenosis, number of balloon dilatations needed and other surgical interventions. On the other hand, interval in between surgeries was found to be longer in patients without an intubation history, and in idiopathic SGS (p = 0.004, p = 0.015, respectively). There was no significant relationship between surgical interval and gender, BMI, length of stenosis, grade (p = 0.059, p = 0.47, p = 0.97, p = 0.36, respectively). Airway stenosis in adults is complicated by the presence of multiple comorbidities. Better understanding of the etiology could aid in the prevention of the injury before it forms.

Entities:  

Keywords:  Adult subglottic stenosis; Comorbidity; Endoscopic dilatation; Laryngotracheal stenosis; Outcomes

Mesh:

Year:  2015        PMID: 26335288     DOI: 10.1007/s00405-015-3750-2

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  19 in total

1.  Association of airway abnormalities and risk factors in 37 subglottic stenosis patients.

Authors:  David M Poetker; Sandra L Ettema; Joel H Blumin; Robert J Toohill; Albert L Merati
Journal:  Otolaryngol Head Neck Surg       Date:  2006-09       Impact factor: 3.497

2.  Predictive factors of success or failure in the endoscopic management of laryngeal and tracheal stenosis.

Authors:  G T Simpson; M S Strong; G B Healy; S M Shapshay; C W Vaughan
Journal:  Ann Otol Rhinol Laryngol       Date:  1982 Jul-Aug       Impact factor: 1.547

3.  Evidence of extraesophageal reflux in idiopathic subglottic stenosis.

Authors:  Joel H Blumin; Nikki Johnston
Journal:  Laryngoscope       Date:  2011-05-06       Impact factor: 3.325

4.  Role of balloon dilation in the management of adult idiopathic subglottic stenosis.

Authors:  Kenneth H Lee; Michael J Rutter
Journal:  Ann Otol Rhinol Laryngol       Date:  2008-02       Impact factor: 1.547

Review 5.  Endocrine aspects of obstructive sleep apnea.

Authors:  Pierre Attal; Philippe Chanson
Journal:  J Clin Endocrinol Metab       Date:  2010-01-08       Impact factor: 5.958

6.  Effect of hyperglycemia on triggering of transient lower esophageal sphincter relaxations.

Authors:  Qing Zhang; Michael Horowitz; Rachael Rigda; Christopher Rayner; Andrew Worynski; Richard H Holloway
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2004-05       Impact factor: 4.052

7.  The prevalence of diabetes in a series of patients with subglottic stenosis.

Authors:  Sandra L Ettema; Todd A Loerhl; Robert J Toohill; Albert L Merati
Journal:  Ear Nose Throat J       Date:  2007-11       Impact factor: 1.697

8.  Groningen dilatation tracheoscope in treatment of moderate subglottic and tracheal stenosis.

Authors:  György B Halmos; Bernard F A M van der Laan; Frederik G Dikkers
Journal:  Ann Otol Rhinol Laryngol       Date:  2009-05       Impact factor: 1.547

9.  Endoscopic cold incision, balloon dilation, mitomycin C application, and steroid injection for adult laryngotracheal stenosis.

Authors:  Noah P Parker; Dipankar Bandyopadhyay; Stephanie Misono; George S Goding
Journal:  Laryngoscope       Date:  2012-10-19       Impact factor: 3.325

10.  Laryngeal injury from prolonged endotracheal intubation.

Authors:  E A Weymuller
Journal:  Laryngoscope       Date:  1988-08       Impact factor: 3.325

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  4 in total

1.  Health Care Costs and Cost-effectiveness in Laryngotracheal Stenosis.

Authors:  Linda X Yin; William V Padula; Shekhar Gadkaree; Kevin Motz; Sabrina Rahman; Zachary Predmore; Alexander Gelbard; Alexander T Hillel
Journal:  Otolaryngol Head Neck Surg       Date:  2018-11-27       Impact factor: 3.497

2.  Analysis of Age-Related Differences of Risk Factors and Comorbidities in Laryngotracheal Stenosis Patients.

Authors:  Mehmet Burak Asik; Hakan Birkent
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2018-05-02

3.  Prevalence and incidence of idiopathic subglottic stenosis in southern and central Alberta: a retrospective cohort study.

Authors:  Ryan K Chan; Beau Ahrens; Paul MacEachern; J Douglas Bosch; Derrick R Randall
Journal:  J Otolaryngol Head Neck Surg       Date:  2021-11-12

Review 4.  Impact of gastroesophageal reflux in the pathogenesis of tracheal stenosis.

Authors:  Paulo Francisco Guerreiro Cardoso; Helio Minamoto; Benoit Jacques Bibas; Paulo Manuel Pego-Fernandes
Journal:  Transl Cancer Res       Date:  2020-03       Impact factor: 1.241

  4 in total

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