Ryotaro Tsukue1, Yasumasa Okamoto2, Atsuo Yoshino2, Yoshihiko Kunisato3, Koki Takagaki2, Yoshitake Takebayashi4, Keisuke Tanaka5, Kyohei Konuma1, Ichiro Tsukue1, Shigeto Yamawaki2. 1. Senogawa Hospital, 4-11-13, Nakanohigashi, Akiku, Hiroshima, 739-0323, Japan. 2. Department of Psychiatry and Neurosciences, Division of Frontier Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan. 3. Department of Psychology, School of Human Sciences, Senshu University, Kanagawa, Japan. 4. Risk Analysis Research Center, Institute of Statistical Mathematics, Tokyo, Japan. 5. Career Development Center, Hyogo University of Teacher Education, Hyogo, Japan.
Abstract
BACKGROUND: Alcohol-dependent patients are known to be generally more unfairness sensitive. The ultimatum game (UG) is an experimental task designed to provoke feelings of perceived unfairness. A previous study using the UG has reported more unfairness sensitivity in patients with alcohol dependence than in a nondependent control group; it has been speculated that this increased sensitivity might be due to a difficulty in impulse control. However, the mechanism of this relationship has not been clarified. Therefore, the relationship between unfairness sensitivity in interpersonal relationships and impulsivity was investigated using UG and delay discounting (DD) paradigms. METHODS: Subjects were 32 individuals with alcohol dependency and 36 healthy control individuals; both groups performed UG and DD tasks. RESULTS: Participants with alcohol dependence rejected monetary offers deemed unfair at a significantly higher rate than did control participants. Moreover, the proportion of accepting unfairness was negatively correlated with impulsivity in patients with alcohol dependence. CONCLUSIONS: Perceived unfairness is related to impulsivity in patients with alcohol dependence. These results provide insights concerning the psychopathology of alcohol dependence.
BACKGROUND:Alcohol-dependent patients are known to be generally more unfairness sensitive. The ultimatum game (UG) is an experimental task designed to provoke feelings of perceived unfairness. A previous study using the UG has reported more unfairness sensitivity in patients with alcohol dependence than in a nondependent control group; it has been speculated that this increased sensitivity might be due to a difficulty in impulse control. However, the mechanism of this relationship has not been clarified. Therefore, the relationship between unfairness sensitivity in interpersonal relationships and impulsivity was investigated using UG and delay discounting (DD) paradigms. METHODS: Subjects were 32 individuals with alcohol dependency and 36 healthy control individuals; both groups performed UG and DD tasks. RESULTS:Participants with alcohol dependence rejected monetary offers deemed unfair at a significantly higher rate than did control participants. Moreover, the proportion of accepting unfairness was negatively correlated with impulsivity in patients with alcohol dependence. CONCLUSIONS: Perceived unfairness is related to impulsivity in patients with alcohol dependence. These results provide insights concerning the psychopathology of alcohol dependence.
Authors: Carlos R Cortes; Erica N Grodin; Claire L Mann; Karan Mathur; Michael Kerich; Xi Zhu; Melanie Schwandt; Nancy Diazgranados; David T George; Reza Momenan; Markus Heilig Journal: Alcohol Alcohol Date: 2018-05-01 Impact factor: 2.826