| Literature DB >> 26331799 |
Saïd Rachida1, Peter N Matsapola1, Marianne Wolfaardt1, Maureen B Taylor.
Abstract
Hepatitis A virus (HAV) was detected, by real-time reverse transcription-polymerase chain reaction, in irrigation water from a dam on a commercial fresh produce farm in South Africa (SA). The virus was characterized by nucleotide sequence and phylogenetic analysis of a consensus sequence spanning the VP1 and VP1/P2B genomic regions. Amino acid sequence and phylogenetic analysis indicated that the HAV strain was closely related to HAV genotype V and possibly of simian origin. This suggests that a novel HAV may be circulating in SA and its presence in irrigation water highlights the potential for zoonotic or anthroponotic cross-species transmission via environmental food and water sources.Entities:
Keywords: RT-PCR detection; environment; genotype; non-human primate; phylogenetic tree
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Year: 2015 PMID: 26331799 DOI: 10.1002/jmv.24370
Source DB: PubMed Journal: J Med Virol ISSN: 0146-6615 Impact factor: 2.327