Literature DB >> 26331601

Circadian Dysfunction and Obesity: Is Leptin the Missing Link?

Charna Dibner1, Frédéric Gachon2.   

Abstract

While accumulating evidence suggests that circadian desynchrony is linked to obesity and metabolic syndrome, the underlining mechanism is still poorly understood. In this issue, Kettner et al. (2015) demonstrate that leptin resistance, induced by circadian clock deficiency or chronic jet lag, may represent this missing link.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26331601      PMCID： PMC4657153          DOI： 10.1016/j.cmet.2015.08.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  10 in total

1.  Adverse metabolic and cardiovascular consequences of circadian misalignment.

Authors:  Frank A J L Scheer; Michael F Hilton; Christos S Mantzoros; Steven A Shea
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-02       Impact factor: 11.205

Review 2.  Advances in understanding the interrelations between leptin resistance and obesity.

Authors:  Haitao Pan; Jiao Guo; Zhengquan Su
Journal:  Physiol Behav       Date:  2014-04-12

3.  A circadian gene expression atlas in mammals: implications for biology and medicine.

Authors:  Ray Zhang; Nicholas F Lahens; Heather I Ballance; Michael E Hughes; John B Hogenesch
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-27       Impact factor: 11.205

4.  The molecular clock mediates leptin-regulated bone formation.

Authors:  Loning Fu; Millan S Patel; Allan Bradley; Erwin F Wagner; Gerard Karsenty
Journal:  Cell       Date:  2005-09-09       Impact factor: 41.582

Review 5.  Circadian timing of metabolism in animal models and humans.

Authors:  C Dibner; U Schibler
Journal:  J Intern Med       Date:  2015-02-06       Impact factor: 8.989

6.  Circadian Dysfunction Induces Leptin Resistance in Mice.

Authors:  Nicole M Kettner; Sara A Mayo; Jack Hua; Choogon Lee; David D Moore; Loning Fu
Journal:  Cell Metab       Date:  2015-07-09       Impact factor: 27.287

7.  Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver.

Authors:  Gaspard Cretenet; Mikaël Le Clech; Frédéric Gachon
Journal:  Cell Metab       Date:  2010-01       Impact factor: 27.287

Review 8.  Hypothalamic lipotoxicity and the metabolic syndrome.

Authors:  Pablo B Martínez de Morentin; Luis Varela; Johan Fernø; Rubén Nogueiras; Carlos Diéguez; Miguel López
Journal:  Biochim Biophys Acta       Date:  2009-09-29

9.  Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse.

Authors:  Deanna Marie Arble; Martha Hotz Vitaterna; Fred W Turek
Journal:  PLoS One       Date:  2011-09-19       Impact factor: 3.240

Review 10.  Lipid-dependent regulation of the unfolded protein response.

Authors:  Romain Volmer; David Ron
Journal:  Curr Opin Cell Biol       Date:  2014-12-25       Impact factor: 8.382
  10 in total
  5 in total

Review 1.  Recent evidence in support of traditional chinese medicine to restore normal leptin function in simple obesity.

Authors:  Jialin Shao; Chen Li; Litao Bai; Xiaolin Ni; Shaoqin Ge; Jinghui Zhang; Hanqing Zhao
Journal:  Heliyon       Date:  2022-05-19

Review 2.  Nutrigenetics and Nutrimiromics of the Circadian System: The Time for Human Health.

Authors:  Víctor Micó; Laura Díez-Ricote; Lidia Daimiel
Journal:  Int J Mol Sci       Date:  2016-02-26       Impact factor: 5.923

Review 3.  Unraveling the Role of Leptin in Liver Function and Its Relationship with Liver Diseases.

Authors:  Maite Martínez-Uña; Yaiza López-Mancheño; Carlos Diéguez; Manuel A Fernández-Rojo; Marta G Novelle
Journal:  Int J Mol Sci       Date:  2020-12-09       Impact factor: 5.923

Review 4.  Autonomic Nervous System in Obesity and Insulin-Resistance-The Complex Interplay between Leptin and Central Nervous System.

Authors:  Benedetta Russo; Marika Menduni; Patrizia Borboni; Fabiana Picconi; Simona Frontoni
Journal:  Int J Mol Sci       Date:  2021-05-14       Impact factor: 5.923

5.  Regulation of the MAPK signaling pathway by miR-421-5p in rats under light pollution.

Authors:  Qianwen Ma; Yong Tan; Xuan Chen; Shuping Chen; Yuying Sun; Beibei Zhou
Journal:  Int J Mol Med       Date:  2018-09-13       Impact factor: 4.101
  5 in total

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