Literature DB >> 26328954

Evaluation of a synthetic single-crystal diamond detector for relative dosimetry on the Leksell Gamma Knife Perfexion radiosurgery system.

Pietro Mancosu1, Giacomo Reggiori1, Antonella Stravato1, Anna Gaudino1, Francesca Lobefalo1, Valentina Palumbo1, Piera Navarria2, Anna Ascolese2, Piero Picozzi3, Marco Marinelli4, Gianluca Verona-Rinati4, Stefano Tomatis1, Marta Scorsetti2.   

Abstract

PURPOSE: To evaluate the new commercial PTW-60019 synthetic single-crystal microDiamond detector (PTW, Freiburg, Germany) for relative dosimetry measurements on a clinical Leksell Gamma Knife Perfexion radiosurgery system.
METHODS: Detector output ratios (DORs) for 4 and 8 mm beams were measured using a microDiamond (PTW-60019), a stereotactic unshielded diode [IBA stereotactic field detector (SFD)], a shielded diode (IBA photon field detector), and GafChromic EBT3 films. Both parallel and transversal acquisition directions were considered for PTW-60019 measurements. Measured DORs were compared to the new output factor reference values for Gamma Knife Perfexion (0.814 and 0.900 for 4 and 8 mm, respectively). Profiles in the three directions were also measured for the 4 mm beam to evaluate full width at half maximum (FWHM) and penumbra and to compare them with the corresponding Leksell GammaPlan profiles.
RESULTS: FWHM and penumbra for PTW-60019 differed from the calculated values by less than 0.2 and 0.3 mm, for the parallel and transversal acquisitions, respectively. GafChromic films showed FWHM and penumbra within 0.1 mm. The output ratio obtained with the PTW-60019 for the 4 mm field was 1.6% greater in transverse direction compared to the nominal value. Comparable differences up to 0.8% and 1.0% for, respectively, GafChromic films and SFD were found.
CONCLUSIONS: The microDiamond PTW-60019 is a suitable detector for commissioning and routine use of Gamma Knife with good agreement of both DORs and profiles in the three directions.

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Year:  2015        PMID: 26328954     DOI: 10.1118/1.4927569

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

Review 1.  Stereotactic radiosurgery alone for multiple brain metastases? A review of clinical and technical issues.

Authors:  Arjun Sahgal; Mark Ruschin; Lijun Ma; Wilko Verbakel; David Larson; Paul D Brown
Journal:  Neuro Oncol       Date:  2017-04-01       Impact factor: 12.300

2.  Replacing gamma knife beam-profiles on film with point-detector scans.

Authors:  Benedikt Rudek; Kenneth Bernstein; Sunshine Osterman; Tanxia Qu
Journal:  J Appl Clin Med Phys       Date:  2022-01-09       Impact factor: 2.102

3.  Different Dosimeters/Detectors Used in Small-Field Dosimetry: Pros and Cons.

Authors:  Wrya Parwaie; Soheila Refahi; Mahdieh Afkhami Ardekani; Bagher Farhood
Journal:  J Med Signals Sens       Date:  2018 Jul-Sep
  3 in total

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