Literature DB >> 26328101

The impact of diabetes mellitus on penile length in men undergoing inflatable penile prosthesis implantation.

Yiğit Akın1, İlker Fatih Şahiner2, Mustafa Faruk Usta2.   

Abstract

OBJECTIVE: To evaluate the changing cavernosal length of patients with diabetes mellitus (DM) and organic erectile dysfunction (ED) who were treated with inflatable, three-piece penile prostheses, a current surgical treatment option in our clinic, over the course of 12 years.
MATERIALS AND METHODS: Between April 2000 and December 2012, we retrospectively investigated data from patients who were diagnosed with organic ED and undergone penile prosthesis implantation (PPI). Of the 239 patients, 235 of them were included in the study. Four patients who were operated on for trans-sexuality were excluded from the study. All patients were divided into two groups as those with (Group 1) or without DM (Group 2). Data, including age, body mass index (BMI) in kg/m(2), surgical history, comorbidities, International Index of Erectile Function (IIEF) questionnaire scores, combined intracavernous injection and stimulation (CIS) test results, length of corpus cavernosum while implanting the penile prosthesis, complications, operative times, mean hospital stay, and satisfaction of the patient and partner, were recorded. Kruskal-Wallis and Mann-Whitney U tests were used for statistical analysis. A p-value of <0.05 was considered to be statistically signifcant.
RESULTS: The mean age was 57.9±10.5 years. Study population consisted of patients with DM (n=65), hypertension (n=21), DM, and hypertension (n=28), hyperlipidemia (n=5), a history of previous radical pelvic surgery with (n=4) or without DM (n=51) or cases without any comorbidity (n=62). Mean length of the corpus cavernosum was 17.277±0.1509 cm in Group 1 and 17289±0.1598 cm in Group 2 (p<0.05). Additionally, the other parameters, including age, operative time, and the satisfaction of the patient and partner, were not different between these groups (p>0.05).
CONCLUSION: The length of the corpus cavernosum and the destruction of cavernosal tissues do not depend only on DM. We conclude that these features may have multifactorial causes.

Entities:  

Keywords:  Corpus cavernosum; diabetes mellitus; erectile dysfunction; penile prosthesis; penis

Year:  2013        PMID: 26328101      PMCID: PMC4548619          DOI: 10.5152/tud.2013.033

Source DB:  PubMed          Journal:  Turk J Urol        ISSN: 2149-3235


  23 in total

Review 1.  Clinical review 135: The importance of beta-cell failure in the development and progression of type 2 diabetes.

Authors:  S E Kahn
Journal:  J Clin Endocrinol Metab       Date:  2001-09       Impact factor: 5.958

Review 2.  Surgical approaches for penile prosthesis implantation: penoscrotal vs infrapubic.

Authors:  D K Montague; K W Angermeir
Journal:  Int J Impot Res       Date:  2003-10       Impact factor: 2.896

3.  Penile prosthesis infections.

Authors:  D K Montague; K W Angermeier; M M Lakin
Journal:  Int J Impot Res       Date:  2001-12       Impact factor: 2.896

4.  Serial assessment of efficacy and satisfaction profiles following penile prosthesis surgery.

Authors:  John P Mulhall; Absaar Ahmed; Jeffrey Branch; Marilyn Parker
Journal:  J Urol       Date:  2003-04       Impact factor: 7.450

5.  Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy.

Authors:  Trinity J Bivalacqua; Mustafa F Usta; Muammer Kendirci; Leena Pradhan; Xavier Alvarez; Hunter C Champion; Philip J Kadowitz; Wayne J G Hellstrom
Journal:  J Sex Med       Date:  2005-03       Impact factor: 3.802

6.  Summary of the recommendations on sexual dysfunctions in men.

Authors:  Tom F Lue; François Giuliano; Francesco Montorsi; Raymond C Rosen; Karl-Erik Andersson; Stanley Althof; George Christ; Dimitrios Hatzichristou; Mark Hirsch; Yasasuke Kimoto; Ronald Lewis; Kevin McKenna; Chris MacMahon; Alvaro Morales; John Mulcahy; Harin Padma-Nathan; John Pryor; Inigo Saenz de Tejada; Ridwan Shabsigh; Gorm Wagner
Journal:  J Sex Med       Date:  2004-07       Impact factor: 3.802

7.  Antibiotic coating reduces penile prosthesis infection.

Authors:  Dmitry Droggin; Ridwan Shabsigh; Aristotelis G Anastasiadis
Journal:  J Sex Med       Date:  2005-07       Impact factor: 3.802

8.  The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: preventive versus curative treatment.

Authors:  Mustafa F Usta; Muammer Kendirci; Serap Gur; Neale A Foxwell; Trinity J Bivalacqua; Selim Cellek; Wayne J G Hellstrom
Journal:  J Sex Med       Date:  2006-03       Impact factor: 3.802

9.  Changes in the corpora cavernosa of impotent diabetics: comparing histological with clinical findings.

Authors:  M J Jevtich; M Kass; N Khawand
Journal:  J Urol (Paris)       Date:  1985

Review 10.  Diabetes, obesity, and erectile dysfunction.

Authors:  Ronald Tamler
Journal:  Gend Med       Date:  2009
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