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Literature DB >> 26327517

Correction: A Five-Year Experience of Carbapenem Resistance in Enterobacteriaceae Causing Neonatal Septicaemia: Predominance of NDM-1.

Saswati Datta, Subhasree Roy, Somdatta Chatterjee, Anindya Saha, Barsha Sen, Titir Pal, Tapas Som, Sulagna Basu.

Abstract

Entities: Chemical Disease Gene Species

Year: 2015 PMID： 26327517 PMCID： PMC4556661 DOI： 10.1371/journal.pone.0134079

Source DB: PubMed Journal: PLoS One ISSN： 1932-6203 Impact factor: 3.240

× No keyword cloud information.

Gene names Ompk36 and Ompk35 are swapped incorrectly throughout the manuscript. All instances of Ompk35 should appear as Ompk36, and all instances of Ompk36 should appear as Ompk35. Corrected versions of Tables 3 and 4, which contain references to Ompk35, can be viewed below with the correct references to Ompk36.

Table 3

Microbiological and molecular characterization of non-NDM-harbouring Enterobacteriaceae isolates with ertapenem MIC ≥0.5 mg/L.

Isolate no.	Period of isolation	organism	MIC Values (mg/L)								Genetic determinants	Integrons	Porins
Isolate no.	Period of isolation	organism	CT	ETP	MP	AK	GM	CI	TGC	CL	Genetic determinants	Integrons	Porins
I1	Mar, 2007	Klebsiella pneumoniae	>256	0.5	0.094	8	96	3	ND ^#	ND	bla _SHV-28, bla _TEM-1, bla _OXA-1, bla _CTX-M-28		Ompk36, Omp A
I2	Aug, 2007	Klebsiella pneumoniae	>256	0.5	0.094	24	13	4	ND	ND	bla _SHV-61, bla _TEM-1, bla _OXA-1, bla _CTXM-22	IntI1	Ompk36, Omp A
I3	Aug, 2007	Escherichia coli	>256	0.5	0.19	16	128	>32	ND	ND	bla _OXA-1, bla _CTXM-28, rmt B		Omp C, Omp A
I4	Sep, 2007	Enterobacter cloacae	>256	0.5	0.19	≥256	≥1024	>32	ND	ND	bla _TEM-1, bla _OXA-1, bla _CTXM-15		Omp C, Omp A
I5	Jan, 2008	Enterobacter cloacae	>256	24	0.25	16	≥1024	>32	0.125	0.25	bla _TEM-1, bla _OXA-1, bla _CTXM-15, bla _ACT-7		Omp C, Omp A
I6	Sep, 2008	Klebsiella pneumoniae	>256	0.5	0.047	12	162	>32	0.5	0.16	bla _TEM-1, bla _OXA-1, bla _CTXM-15	IntI1	Ompk36, Omp A
I7	Dec, 2008	Escherichia coli	>256	>32	1	≥256	≥1024	>32	0.064	0.125	bla _TEM-1, bla _OXA-1, bla _CTXM-15, bla _CMY-4	IntI1	Omp C, Omp A
I8	Jan, 2009	Klebsiella pneumoniae	>256	2	0.19	8	48	>32	8	1	bla _SHV-11, bla _TEM-1, bla _OXA-1, bla _CTXM-15	IntI1	Ompk36, Omp A
I9	Jul, 2009	Klebsiella pneumoniae	>256	32	0.125	8	128	>32	1	0.38	bla _SHV-1, bla _TEM-1, bla _OXA-1, bla _CTXM-15	IntI1	Ompk36, Omp A
I10	Aug, 2009	Klebsiella pneumoniae	>256	1	0.125	2	>1024	>32	1	0.25	bla _SHV-1, bla _TEM-1, bla _OXA-1, bla _CTXM-15		Ompk36, Omp A
I11	Dec, 2009	Klebsiella pneumoniae	>256	0.5	0.38	2	0.75	0.75	0.75	0.5	bla _SHV-1	IntI1	Ompk36, Omp A

CT: Cefotaxime, ETP: Ertapenem, MP: Meropenem, AK: Amikacin, GM: Gentamicin, CI: Ciprofloxacin, TGC: Tigecycline, CL: Colistin; IntI1: class 1 integron; Omp: Outer membrane protein.

# ND: Not Determined

Table 4

Antibiotic susceptibility and molecular characterization of NDM-1- harbouring Enterobacteriaceae along with clinical features of the neonates harbouring the same isolates in their blood specimens.

Patient no./Organism(isolate no.)	Sex	InbornOrOutborn	Birthweight	GestationalAge ^$	ModeOfdelivery	ventilation	Prescribedantibiotics	Outcome	MIC Values (mg/L)								Geneticdeterminants	Integron	Porins
Patient no./Organism(isolate no.)	Sex	InbornOrOutborn	Birthweight	GestationalAge ^$	ModeOfdelivery	ventilation	Prescribedantibiotics	Outcome	CT	ETP	MP	AK	GM	CI	TGC	CL	Geneticdeterminants	Integron	Porins
P1/ Escherichia coli (E1)	M	Inborn	LBW	preterm	LUCS	No	PipTaz/Amika	discharge	>256	>32	>32	>256	>1024	>32	0.25	1	bla _TEM-1, bla _CTXM-₁₅,bla _CMY-6, rmt C, aac(6’)-Ib, ble _MBL	IntI1	Omp C, Omp A
P2/ Escherichia coli (E2)	M	Inborn	VLBW	preterm	LUCS	Yes	PipTaz/Amika	discharge	>256	>32	8	>256	>1024	>32	0.25	0.5	bla _TEM-1, bla _OXA-1, bla _CMY-42, arm A, aac(6’)-Ib-cr, ble _MBL		Omp C, Omp F, Omp A
P3/ Klebsiella pneumoniae (K1)	M	Outborn	NW	term	NVD	Yes	colistin	discharge	>256	>32	32	>256	>1024	>32	0.75	0.25	bla _SHV-11, aac(6’)-Ib, ble _MBL	IntI1	Ompk36, Omp A
P4/ Klebsiella pneumoniae (K2)	M	Outborn	LBW	preterm	LUCS	No	ofloxacin	discharge	>256	>32	24	>256	>1024	3	1.5	0.38	bla _SHV-167, bla _CTXM-₁₅,arm A, aac(6’)-Ib-cr, ble _MBL	IntI1	Ompk36, Omp A
P5/ Klebsiella pneumoniae (K3)	M	Outborn	LBW	preterm	NVD	Yes	ofloxacin	discharge	>256	12	4	>256	>1024	>32	1	0.75	bla _TEM-1, bla _OXA-1, bla _CTXM-₁₅, aac(6’)-Ib, ble _MBL	IntI1	Ompk36, Omp A
P6/ Klebsiella pneumoniae (K4)	M	Outborn	LBW	term	LUCS	Yes	colistin	discharge	>256	>32	32	>256	>1024	>32	1	0.38	bla _TEM-1, bla _OXA-1, bla _CTXM-₁₅, aac(6’)-Ib, ble _MBL	IntI1	Ompk36, Omp A
P7/ Escherichia coli (E3)	M	Inborn	LBW	preterm	NVD	No	meropenem	death	>256	>32	16	>256	>1024	>32	0.25	0.38	bla _TEM-1, bla _CTXM-₁₅, rmt B, ble _MBL	IntI1	Omp C, Omp F, Omp A
P8/ Klebsiella pneumoniae (K5)	F	Outborn	VLBW	preterm	LUCS	Yes	meropenem	discharge	>256	>32	32	>256	>1024	>32	0.38	0.75	bla _SHV-11, bla _OXA-1, bla _CTXM-₁₅, aac(6’)-Ib, ble _MBL	IntI1	Ompk36, Omp A
P9/ Enterobacter cloacae (EC1)	M	Outborn	LBW	preterm	NVD	Yes	colistin/ofloxacin	LAMA	>256	>32	>32	>256	>1024	4	0.25	1.5	bla _OXA-1, bla _CTXM-₁₅, bla _ACT-16, rmt C, aac(6’)-Ib, ble _MBL	IntI1	Omp C, Omp A
P10/ Enterobacter cloacae (EC2)*	M	Outborn	VLBW	preterm	NVD	Yes	colistin	discharge	>256	8	6	>256	>1024	2	0.5	0.5	bla _TEM-1, bla _OXA-1, bla _CTXM-₁₅, rmt B, aac(6’)-Ib-cr, ble _MBL	IntI1	Omp C, Omp A
P10/ Escherichia coli (E4)*	M	Outborn	VLBW	preterm	NVD	Yes	colistin	discharge	>256	>32	>32	>256	>1024	>32	0.125	0.75	bla _TEM-1, bla _CTXM-₁₅, bla _CMY-42, rmt B, ble _MBL	IntI1	Omp C, Omp F, Omp A
P11/ Escherichia coli (E5)	M	Inborn	LBW	term	LUCS	No	ofloxacin	discharge	>256	>32	32	>256	>1024	>32	0.38	1.5	bla _CTXM-₁₅, rmt B, aac(6’)-Ib-cr, ble _MBL	IntI1	Omp C, Omp F, Omp A
P12/ Klebsiella pneumoniae (K6)**	No clinical data available								>256	12	4	>256	>1024	8	0.75	1	bla _TEM-1, bla _OXA-1, bla _CTXM-₁₅,rmt B,aac(6’)-Ib,ble _MBL	IntI1	Ompk36,Omp A
P13/ Enterobacter cloacae (EC3)	M	Outborn	VLBW	preterm	NVD	Yes	PipTaz/Amika	death	>256	>32	32	>256	>1024	8	1.5	1	bla _TEM-1, bla _CTXM-₁₅, aac(6’)-Ib, ble _MBL	IntI1	Omp C, Omp A
P14/ Escherichia coli (E6)	M	Outborn	VLBW	preterm	NVD	No	ofloxacin	discharge	>256	>32	1.5	>256	>1024	>32	0.094	0.75	bla _TEM-1, bla _OXA-1, bla _CTXM-₁₅, bla _CMY-42, rmt B, aac(6’)-Ib	IntI1	Omp C, Omp F, Omp A

M: male; F: female; LBW: low birth weight (<2500 gm); VLBW: very low birth weight (<1500 gm); NW: normal weight (>2500 gm); NVD: normal vaginal delivery; LUCS: low uterine caesarean delivery; Omp: Outer membrane protein; LAMA: left against medical advice.

CT: Cefotaxime; ETP: Ertapenem; MP: Meropenem; AK: Amikacin; GM: Gentamicin; CI: Ciprofloxacin; TGC: Tigecycline; CL: Colistin; PipTaz: Piperacillin/Tazobactam; Amika: Amikacin

$ Gestational age <37 weeks is considered as preterm.

*Two different Enterobacteriaceae isolates (1 E. coli and 1 E. cloacae) were isolated from blood of a single patient.

**No clinical data was available for this patient

CT: Cefotaxime, ETP: Ertapenem, MP: Meropenem, AK: Amikacin, GM: Gentamicin, CI: Ciprofloxacin, TGC: Tigecycline, CL: Colistin; IntI1: class 1 integron; Omp: Outer membrane protein. # ND: Not Determined M: male; F: female; LBW: low birth weight (<2500 gm); VLBW: very low birth weight (<1500 gm); NW: normal weight (>2500 gm); NVD: normal vaginal delivery; LUCS: low uterine caesarean delivery; Omp: Outer membrane protein; LAMA: left against medical advice. CT: Cefotaxime; ETP: Ertapenem; MP: Meropenem; AK: Amikacin; GM: Gentamicin; CI: Ciprofloxacin; TGC: Tigecycline; CL: Colistin; PipTaz: Piperacillin/Tazobactam; Amika: Amikacin $ Gestational age <37 weeks is considered as preterm. *Two different Enterobacteriaceae isolates (1 E. coli and 1 E. cloacae) were isolated from blood of a single patient. **No clinical data was available for this patient

1 in total

1. A five-year experience of carbapenem resistance in Enterobacteriaceae causing neonatal septicaemia: predominance of NDM-1.

Authors: Saswati Datta; Subhasree Roy; Somdatta Chatterjee; Anindya Saha; Barsha Sen; Titir Pal; Tapas Som; Sulagna Basu
Journal: PLoS One Date: 2014-11-18 Impact factor: 3.240

1 in total

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2. Extended-spectrum β-lactamase & carbapenemase-producing Gram-negative bacilli in neonates from a tertiary care centre in Dibrugarh, Assam, India.

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2 in total

Correction: A Five-Year Experience of Carbapenem Resistance in Enterobacteriaceae Causing Neonatal Septicaemia: Predominance of NDM-1.

1. A five-year experience of carbapenem resistance in Enterobacteriaceae causing neonatal septicaemia: predominance of NDM-1.

1. Transcriptional analysis of blaNDM-1 and copy number alteration under carbapenem stress.

2. Extended-spectrum β-lactamase & carbapenemase-producing Gram-negative bacilli in neonates from a tertiary care centre in Dibrugarh, Assam, India.

1. Transcriptional analysis of bla_NDM-1 and copy number alteration under carbapenem stress.