Literature DB >> 26327359

The Spot 42 RNA: A regulatory small RNA with roles in the central metabolism.

Cecilie Bækkedal1, Peik Haugen1.   

Abstract

The Spot 42 RNA is a 109 nucleotide long (in Escherichia coli) noncoding small regulatory RNA (sRNA) encoded by the spf (spot fourty-two) gene. spf is found in gamma-proteobacteria and the majority of experimental work on Spot 42 RNA has been performed using E. coli, and recently Aliivibrio salmonicida. In the cell Spot 42 RNA plays essential roles as a regulator in carbohydrate metabolism and uptake, and its expression is activated by glucose, and inhibited by the cAMP-CRP complex. Here we summarize the current knowledge on Spot 42, and present the natural distribution of spf, show family-specific secondary structural features of Spot 42, and link highly conserved structural regions to mRNA target binding.

Entities:  

Keywords:  Spot 42; gamma proteobacteria; non-coding RNA; pirin; sRNA; small RNA; spf

Mesh：

Substances：

Year:  2015        PMID： 26327359      PMCID： PMC4829326          DOI： 10.1080/15476286.2015.1086867

Source DB:  PubMed          Journal:  RNA Biol        ISSN： 1547-6286            Impact factor:   4.652


  25 in total

1.  A small, unstable RNA molecule of Escherichia coli: spot 42 RNA. II. Accumulation and distribution.

Authors:  B G Sahagan; J E Dahlberg
Journal:  J Mol Biol       Date:  1979-07-05       Impact factor: 5.469

2.  DNA polymerase I activity in Escherichia coli is influenced by spot 42 RNA.

Authors:  D A Polayes; P W Rice; J E Dahlberg
Journal:  J Bacteriol       Date:  1988-05       Impact factor: 3.490

3.  Small ribonucleic acids of Escherichia coli. I. Characterization by polyacrylamide gel electrophoresis and fingerprint analysis.

Authors:  T Ikemura; J E Dahlberg
Journal:  J Biol Chem       Date:  1973-07-25       Impact factor: 5.157

4.  Small ribonucleic acids of Escherichia coli. II. Noncoordinate accumulation during stringent control.

Authors:  T Ikemura; J E Dahlberg
Journal:  J Biol Chem       Date:  1973-07-25       Impact factor: 5.157

5.  A small, unstable RNA molecule of Escherichia coli: spot 42 RNA. I. Nucleotide sequence analysis.

Authors:  B G Sahagan; J E Dahlberg
Journal:  J Mol Biol       Date:  1979-07-05       Impact factor: 5.469

6.  Jalview Version 2--a multiple sequence alignment editor and analysis workbench.

Authors:  Andrew M Waterhouse; James B Procter; David M A Martin; Michèle Clamp; Geoffrey J Barton
Journal:  Bioinformatics       Date:  2009-01-16       Impact factor: 6.937

7.  Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon.

Authors:  Thorleif Møller; Thomas Franch; Christina Udesen; Kenn Gerdes; Poul Valentin-Hansen
Journal:  Genes Dev       Date:  2002-07-01       Impact factor: 11.361

8.  A gene between polA and glnA retards growth of Escherichia coli when present in multiple copies: physiological effects of the gene for spot 42 RNA.

Authors:  P W Rice; J E Dahlberg
Journal:  J Bacteriol       Date:  1982-12       Impact factor: 3.490

9.  Cyclic AMP-cyclic AMP receptor protein as a repressor of transcription of the spf gene of Escherichia coli.

Authors:  D A Polayes; P W Rice; M M Garner; J E Dahlberg
Journal:  J Bacteriol       Date:  1988-07       Impact factor: 3.490

10.  Identification of differentially expressed small non-coding RNAs in the legume endosymbiont Sinorhizobium meliloti by comparative genomics.

Authors:  Coral del Val; Elena Rivas; Omar Torres-Quesada; Nicolás Toro; José I Jiménez-Zurdo
Journal:  Mol Microbiol       Date:  2007-10-25       Impact factor: 3.501
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  8 in total

1.  Spot 42 RNA regulates putrescine catabolism in Escherichia coli by controlling the expression of puuE at the post-transcription level.

Authors:  Xin Sun; Ruyan Li; Guochen Wan; Wanli Peng; Shuangjun Lin; Zixin Deng; Rubing Liang
Journal:  J Microbiol       Date:  2021-02-01       Impact factor: 3.422

2.  Mfd regulates RNA polymerase association with hard-to-transcribe regions in vivo, especially those with structured RNAs.

Authors:  Mark N Ragheb; Christopher Merrikh; Kaitlyn Browning; Houra Merrikh
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-05       Impact factor: 12.779

3.  The Small RNA ncS35 Regulates Growth in Burkholderia cenocepacia J2315.

Authors:  Sanne Kiekens; Andrea Sass; Filip Van Nieuwerburgh; Dieter Deforce; Tom Coenye
Journal:  mSphere       Date:  2018-01-10       Impact factor: 4.389

4.  Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism.

Authors:  Andrea Sass; Sanne Kiekens; Tom Coenye
Journal:  Sci Rep       Date:  2017-11-15       Impact factor: 4.379

5.  Dual-function Spot 42 RNA encodes a 15-amino acid protein that regulates the CRP transcription factor.

Authors:  Jordan J Aoyama; Medha Raina; Aoshu Zhong; Gisela Storz
Journal:  Proc Natl Acad Sci U S A       Date:  2022-03-03       Impact factor: 12.779

6.  Synthetic Genetic Interactions Reveal a Dense and Cryptic Regulatory Network of Small Noncoding RNAs in Escherichia coli.

Authors:  Kenneth Rachwalski; Michael J Ellis; Madeline Tong; Eric D Brown
Journal:  mBio       Date:  2022-08-03       Impact factor: 7.786

7.  Codon usage and modular interactions between messenger RNA coding regions and small RNAs in Escherichia coli.

Authors:  Mario Tello; Felipe Avalos; Omar Orellana
Journal:  BMC Genomics       Date:  2018-09-06       Impact factor: 3.969

8.  Differential evolution in 3'UTRs leads to specific gene expression in Staphylococcus.

Authors:  Pilar Menendez-Gil; Carlos J Caballero; Arancha Catalan-Moreno; Naiara Irurzun; Inigo Barrio-Hernandez; Isabelle Caldelari; Alejandro Toledo-Arana
Journal:  Nucleic Acids Res       Date:  2020-03-18       Impact factor: 16.971
  8 in total

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