| Literature DB >> 26325631 |
David Price1, Pete Smith2, Peter Hellings3, Nikos Papadopoulos4, Wytske Fokkens5, Antonella Muraro6, Ruth Murray7, Alison Chisholm8, Pascal Demoly9, Glenis Scadding10, Joaquim Mullol11, Phil Lieberman12, Claus Bachert13, Ralph Mösges14, Dermot Ryan15, Jean Bousquet16,17,18.
Abstract
There are many obstacles in the path of effective allergy management, in general, and allergic rhinitis (AR) control, in particular. Chief among them are: insufficient symptom relief in some patients provided by some currently considered first-line AR treatments in real life; an over-reliance on randomized controlled trials to direct AR guideline recommendations; the need for a broader interpretation of the AR evidence base (to include randomized controlled trials and real-life studies); poorly designed and interpreted studies; and lack of an AR control concept and common language of control. These controversies are fully reviewed here and challenging solutions have been presented.Entities:
Keywords: allergic rhinitis; clinical relevance; control; guidelines; randomized controlled trials; real life
Mesh:
Year: 2015 PMID: 26325631 DOI: 10.1586/1744666X.2015.1081814
Source DB: PubMed Journal: Expert Rev Clin Immunol ISSN: 1744-666X Impact factor: 4.473