María Gracia Sarrión Pérez1, José V Bagán2, Yolanda Jiménez3, María Margaix4, Cristina Marzal5. 1. Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain. Electronic address: m.gracia.sarrion@uv.es. 2. Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain; Department of Stomatology and Maxillofacial Surgery (Head of the Department: José V Bagán, MD, DDS, PhD), University General Hospital, 2 Tres Cruces Avenue, 46014, Valencia, Spain. Electronic address: bagan@uv.es. 3. Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain. Electronic address: yolanda.jimenez@uv.es. 4. Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain. Electronic address: maria.margaix@gmail.com. 5. Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain. Electronic address: cristina.marzal@uv.es.
Abstract
PURPOSE: Imaging techniques such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) are often used to complement the clinical exploration and staging of oral squamous cell carcinoma (OSCC). Which of these techniques is best in establishing correct staging and treatment planning is not clear, however. This study aims to determine which technique is most appropriate for diagnosing the primary tumor and for detecting bone invasion and neck metastases. MATERIAL AND METHODS: A Medline literature search was made over the last 10 years. In each selected study, we recorded the sample size and sensitivity, specificity and precision. Strengths and limitations of each study were assessed also. RESULTS: Eight articles relating to detection of the primary tumor, 19 to bone invasion, and 28 to neck metastases were selected and compared. CONCLUSION: Despite the high precision of positron emission tomography (PET) or hybrid techniques in detecting the primary tumor, they have not replaced magnetic resonance imaging (MRI) or computed tomography (CT), particularly in the case of small lesions. MRI and CT are adequate techniques in the assessment of bone invasion.Recent studies have shown good results with PET-CT and cone-beam CT, but future studies are needed to demonstrate their benefits. Despite the high precision of PET and PET-CT, their use in assessing neck metastases remains subject to controversy, and their use in all patients with OSCC is not justified. CT and MRI are useful in determining the N category.
PURPOSE: Imaging techniques such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) are often used to complement the clinical exploration and staging of oral squamous cell carcinoma (OSCC). Which of these techniques is best in establishing correct staging and treatment planning is not clear, however. This study aims to determine which technique is most appropriate for diagnosing the primary tumor and for detecting bone invasion and neck metastases. MATERIAL AND METHODS: A Medline literature search was made over the last 10 years. In each selected study, we recorded the sample size and sensitivity, specificity and precision. Strengths and limitations of each study were assessed also. RESULTS: Eight articles relating to detection of the primary tumor, 19 to bone invasion, and 28 to neck metastases were selected and compared. CONCLUSION: Despite the high precision of positron emission tomography (PET) or hybrid techniques in detecting the primary tumor, they have not replaced magnetic resonance imaging (MRI) or computed tomography (CT), particularly in the case of small lesions. MRI and CT are adequate techniques in the assessment of bone invasion.Recent studies have shown good results with PET-CT and cone-beam CT, but future studies are needed to demonstrate their benefits. Despite the high precision of PET and PET-CT, their use in assessing neck metastases remains subject to controversy, and their use in all patients with OSCC is not justified. CT and MRI are useful in determining the N category.
Authors: Yasmin Ghantous; Mohamed Omar; Esther Channah Broner; Nishant Agrawal; Alexander T Pearson; Ari J Rosenberg; Vasudha Mishra; Alka Singh; Imad Abu El-Naaj; Peter A Savage; David Sidransky; Luigi Marchionni; Evgeny Izumchenko Journal: Int J Cancer Date: 2021-10-14 Impact factor: 7.396
Authors: Ning Li; Meng-Meng Jie; Min Yang; Li Tang; Si-Yuan Chen; Xue-Mei Sun; Bo Tang; Shi-Ming Yang Journal: Nanoscale Res Lett Date: 2018-04-18 Impact factor: 4.703
Authors: Andreea Nae; Gerard O'Leary; Linda Feeley; Cassie Fives; Brendan Fitzgerald; Elena Chiriac; Patrick Sheahan Journal: World J Otorhinolaryngol Head Neck Surg Date: 2019-03-22