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Literature DB >> 26323715

BigBWA: approaching the Burrows-Wheeler aligner to Big Data technologies.

José M Abuín¹, Juan C Pichel¹, Tomás F Pena¹, Jorge Amigo².

Abstract

UNLABELLED: BigBWA is a new tool that uses the Big Data technology Hadoop to boost the performance of the Burrows-Wheeler aligner (BWA). Important reductions in the execution times were observed when using this tool. In addition, BigBWA is fault tolerant and it does not require any modification of the original BWA source code.
AVAILABILITY AND IMPLEMENTATION: BigBWA is available at the project GitHub repository: https://github.com/citiususc/BigBWA.

Mesh：

Year: 2015 PMID： 26323715 DOI： 10.1093/bioinformatics/btv506

Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937

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Cited

25 in total

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2. Clinical and Molecular Findings of Autosomal Recessive Spastic Ataxia of Charlevoix Saguenay: an Iranian Case Series Expanding the Genetic and Neuroimaging Spectra.

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4. Primary and Secondary Microcephaly, Global Developmental Delay, and Seizure in Two Siblings Caused by a Novel Missense Variant in the ZNF335 Gene.

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BigBWA: approaching the Burrows-Wheeler aligner to Big Data technologies.

1. Genome-wide selective sweep analysis of the high-altitude adaptability of yaks by using the copy number variant.

2. Clinical and Molecular Findings of Autosomal Recessive Spastic Ataxia of Charlevoix Saguenay: an Iranian Case Series Expanding the Genetic and Neuroimaging Spectra.

3. Sex-Specific Genomic Region Identification and Molecular Sex Marker Development of Rock Bream (Oplegnathus fasciatus).

4. Primary and Secondary Microcephaly, Global Developmental Delay, and Seizure in Two Siblings Caused by a Novel Missense Variant in the ZNF335 Gene.

Review 5. Rare variant of TBL1XR1 in West syndrome: A case report.

6. Mapping and analysis of a spatiotemporal H3K27ac and gene expression spectrum in pigs.

7. SparkBWA: Speeding Up the Alignment of High-Throughput DNA Sequencing Data.

Review 8. Single-cell Transcriptome Study as Big Data.

9. Genome Wide Prediction, Mapping and Development of Genomic Resources of Mastitis Associated Genes in Water Buffalo.

10. Parallel and Scalable Short-Read Alignment on Multi-Core Clusters Using UPC+.