Literature DB >> 26323123

[Advances in cardiovascular effects of tanshinone II(A)].

Fen-yan Chen, Ren Guo, Bi-kui Zhang.   

Abstract

Cardiovascular diseases, like coronary heart disease and myocardial infarction, are the most common cause of death worldwide. Chinese medicines have demonstrated rich cardioprotective activities for clinical applications. Salvia miltiorrhiza, a very important component of traditional Chinese medicine, can promote blood circulation and relieve blood stasis. Salvia miltiorrhiza is widely used in treatment of cardiovascular and cerebrovascular disease such as coronary heart disease and cerebral infarction ( CI). Tanshinone II(A), the major lipophilic components extracted from the root of S. miltiorrhiza, possesses anti-atherosclerosis, anti-cardiac hypertrophy, anti-oxidant, anti-arrhythmia and so on. This paper discusses current research status of tanshinone II(A) in cardioprotective effects.

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Year:  2015        PMID: 26323123

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  6 in total

Review 1.  Research Progress of Traditional Chinese Medicine in Treatment of Myocardial fibrosis.

Authors:  Chunzhen Ren; Kai Liu; Xinke Zhao; Huan Guo; Yali Luo; Juan Chang; Xiang Gao; Xinfang Lv; Xiaodong Zhi; Xue Wu; Hugang Jiang; Qilin Chen; Yingdong Li
Journal:  Front Pharmacol       Date:  2022-06-08       Impact factor: 5.988

2.  Effect of tanshinone IIA on oxidative stress and apoptosis in a rat model of fatty liver.

Authors:  Guan-Lin Yang; Lian-Qun Jia; Jin Wu; Yi-Xin Ma; Hui-Min Cao; Nan Song; Ni Zhang
Journal:  Exp Ther Med       Date:  2017-09-21       Impact factor: 2.447

3.  Tanshinone IIA promotes cardiac differentiation and improves cell motility by modulating the Wnt/β‑catenin signaling pathway.

Authors:  Kun Li; Xiuyan Wang; Chenxing Fan; Chunxia Wu; Shizheng Li; Hua Liu
Journal:  Mol Med Rep       Date:  2020-06-24       Impact factor: 2.952

4.  Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats.

Authors:  Ruijuan Chen; Wenli Chen; Xiaoling Huang; Qinglin Rui
Journal:  Mol Med Rep       Date:  2021-03-31       Impact factor: 2.952

5.  Adjuvant Chinese Herbal Products for Preventing Ischemic Stroke in Patients with Atrial Fibrillation.

Authors:  Yu-Chiang Hung; Yu-Chen Cheng; Chih-Hsin Muo; Hsienhsueh Elley Chiu; Chun-Ting Liu; Wen-Long Hu
Journal:  PLoS One       Date:  2016-07-18       Impact factor: 3.240

6.  Tanshinone IIA ameliorates non-alcoholic fatty liver disease through targeting peroxisome proliferator-activated receptor gamma and toll-like receptor 4.

Authors:  Lu Huang; Wei Ding; Ming-Qiang Wang; Zheng-Gen Wang; Hong-Hui Chen; Wen Chen; Qiong Yang; Ting-Na Lu; Qing Yang; Ji-Man He
Journal:  J Int Med Res       Date:  2019-08-05       Impact factor: 1.671

  6 in total

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