Literature DB >> 26322320

The EP3 Receptor: Exploring a New Target for Type 2 Diabetes Therapeutics.

Joshua C Neuman1, Michelle E Kimple2.   

Abstract

Entities:  

Year:  2013        PMID： 26322320      PMCID： PMC4551503     

Source DB:  PubMed          Journal:  J Endocrinol Diabetes Obes        ISSN： 2333-6692


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  39 in total

1.  Two isoforms of prostaglandin EP3 receptor exhibiting constitutive activity and agonist-dependent activity in Rho-mediated stress fiber formation.

Authors:  H Hasegawa; M Negishi; H Katoh; A Ichikawa
Journal:  Biochem Biophys Res Commun       Date:  1997-05-29       Impact factor: 3.575

Review 2.  Mechanisms of inhibition of insulin release.

Authors:  G W Sharp
Journal:  Am J Physiol       Date:  1996-12

3.  Gz, a guanine nucleotide-binding protein with unique biochemical properties.

Authors:  P J Casey; H K Fong; M I Simon; A G Gilman
Journal:  J Biol Chem       Date:  1990-02-05       Impact factor: 5.157

4.  Constitutive activity of human prostaglandin E receptor EP3 isoforms.

Authors:  J Jin; G F Mao; B Ashby
Journal:  Br J Pharmacol       Date:  1997-05       Impact factor: 8.739

5.  Cyclooxygenase-2-derived prostaglandin E₂ promotes injury-induced vascular neointimal hyperplasia through the E-prostanoid 3 receptor.

Authors:  Jian Zhang; Fangfang Zou; Juan Tang; Qianqian Zhang; Yanjun Gong; Qingsong Wang; Yujun Shen; Lixia Xiong; Richard M Breyer; Michael Lazarus; Colin D Funk; Ying Yu
Journal:  Circ Res       Date:  2013-04-17       Impact factor: 17.367

6.  Mouse prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA-transfected Chinese hamster ovary cells.

Authors:  A Irie; E Segi; Y Sugimoto; A Ichikawa; M Negishi
Journal:  Biochem Biophys Res Commun       Date:  1994-10-14       Impact factor: 3.575

7.  Two isoforms of the prostaglandin E receptor EP3 subtype different in agonist-independent constitutive activity.

Authors:  H Hasegawa; M Negishi; A Ichikawa
Journal:  J Biol Chem       Date:  1996-01-26       Impact factor: 5.157

8.  Isoforms of the EP3 subtype of human prostaglandin E2 receptor transduce both intracellular calcium and cAMP signals.

Authors:  S An; J Yang; S W So; L Zeng; E J Goetzl
Journal:  Biochemistry       Date:  1994-12-06       Impact factor: 3.162

Review 9.  Molecular mechanisms of diverse actions of prostanoid receptors.

Authors:  M Negishi; Y Sugimoto; A Ichikawa
Journal:  Biochim Biophys Acta       Date:  1995-10-26

10.  Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

Authors:  Michelle E Kimple; Mark P Keller; Mary R Rabaglia; Renee L Pasker; Joshua C Neuman; Nathan A Truchan; Harpreet K Brar; Alan D Attie
Journal:  Diabetes       Date:  2013-01-24       Impact factor: 9.461
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  5 in total

1.  Prostaglandin EP3 Receptor Antagonists May Provide Novel Treatment for Diabetes.

Authors:  Ahmed F Abdel-Magid
Journal:  ACS Med Chem Lett       Date:  2015-05-13       Impact factor: 4.345

2.  PGE2 -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.

Authors:  Xixi Tao; Ronglu Du; Shumin Guo; Xiangling Feng; Tingting Yu; Qian OuYang; Qiaoli Chen; Xutong Fan; Xueqi Wang; Chen Guo; Xiaozhou Li; Fengxia Xue; Shuai Chen; Minghan Tong; Michael Lazarus; Shengkai Zuo; Ying Yu; Yujun Shen
Journal:  EMBO J       Date:  2022-07-04       Impact factor: 14.012

3.  Human Islet Expression Levels of Prostaglandin E2 Synthetic Enzymes, But Not Prostaglandin EP3 Receptor, Are Positively Correlated with Markers of β-Cell Function and Mass in Nondiabetic Obesity.

Authors:  Nathan A Truchan; Rachel J Fenske; Harpreet K Sandhu; Alicia M Weeks; Chinmai Patibandla; Benjamin Wancewicz; Samantha Pabich; Austin Reuter; Jeffrey M Harrington; Allison L Brill; Darby C Peter; Randall Nall; Michael Daniels; Margaret Punt; Cecilia E Kaiser; Elizabeth D Cox; Ying Ge; Dawn B Davis; Michelle E Kimple
Journal:  ACS Pharmacol Transl Sci       Date:  2021-06-16

Review 4.  Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment.

Authors:  Joshua C Neuman; Rachel J Fenske; Michelle E Kimple
Journal:  Nutr Healthy Aging       Date:  2017-03-31

5.  Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance.

Authors:  Jaclyn A Wisinski; Austin Reuter; Darby C Peter; Michael D Schaid; Rachel J Fenske; Michelle E Kimple
Journal:  Am J Physiol Endocrinol Metab       Date:  2021-07-06       Impact factor: 4.310
  5 in total

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