| Literature DB >> 2632217 |
R G Gugova1, Z D Raikov, S G Zakhariev, G D Demirov, D K Todorov, M V Ilarionova.
Abstract
1-Methyl-1-(2-chloroethyl)-4-nitroso-4-(2-chloroethyl)semicarbazide, 1,1-di-(2-chloroethyl)-4-nitroso-4-(2-chloroethyl)semicarbazide and 1,1-di-(2-bromoethyl)-4-nitroso-4-(2-chloroethyl)semicarbazide, which are a novel class of nitrosoureas containing hydrazinomustard residue, have been synthesized. A dose-dependent antitumour activity was found with the three tested compounds.Entities:
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Year: 1989 PMID: 2632217
Source DB: PubMed Journal: Drugs Exp Clin Res ISSN: 0378-6501