Literature DB >> 26321183

mRNA: Fulfilling the Promise of Gene Therapy.

Drew Weissman1, Katalin Karikó2.   

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Year:  2015        PMID： 26321183      PMCID： PMC4817894          DOI： 10.1038/mt.2015.138

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  12 in total

1.  Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells.

Authors:  Gary K Koski; Katalin Karikó; Shuwen Xu; Drew Weissman; Peter A Cohen; Brian J Czerniecki
Journal:  J Immunol       Date:  2004-04-01       Impact factor: 5.422

2.  Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.

Authors:  Katalin Karikó; Michael Buckstein; Houping Ni; Drew Weissman
Journal:  Immunity       Date:  2005-08       Impact factor: 31.745

3.  Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides.

Authors:  Sandra S Diebold; Catherine Massacrier; Shizuo Akira; Carine Paturel; Yannis Morel; Caetano Reis e Sousa
Journal:  Eur J Immunol       Date:  2006-12       Impact factor: 5.532

4.  Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.

Authors:  Katalin Karikó; Hiromi Muramatsu; Frank A Welsh; János Ludwig; Hiroki Kato; Shizuo Akira; Drew Weissman
Journal:  Mol Ther       Date:  2008-09-16       Impact factor: 11.454

5.  Expression of therapeutic proteins after delivery of chemically modified mRNA in mice.

Authors:  Michael S D Kormann; Günther Hasenpusch; Manish K Aneja; Gabriela Nica; Andreas W Flemmer; Susanne Herber-Jonat; Marceline Huppmann; Lauren E Mays; Marta Illenyi; Andrea Schams; Matthias Griese; Iris Bittmann; Rupert Handgretinger; Dominik Hartl; Joseph Rosenecker; Carsten Rudolph
Journal:  Nat Biotechnol       Date:  2011-01-09       Impact factor: 54.908

6.  Reversal of diabetes insipidus in Brattleboro rats: intrahypothalamic injection of vasopressin mRNA.

Authors:  G F Jirikowski; P P Sanna; D Maciejewski-Lenoir; F E Bloom
Journal:  Science       Date:  1992-02-21       Impact factor: 47.728

7.  Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.

Authors:  Florian Heil; Hiroaki Hemmi; Hubertus Hochrein; Franziska Ampenberger; Carsten Kirschning; Shizuo Akira; Grayson Lipford; Hermann Wagner; Stefan Bauer
Journal:  Science       Date:  2004-02-19       Impact factor: 47.728

8.  Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin.

Authors:  Katalin Karikó; Hiromi Muramatsu; Jason M Keller; Drew Weissman
Journal:  Mol Ther       Date:  2012-02-14       Impact factor: 11.454

9.  Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA.

Authors:  Katalin Karikó; Hiromi Muramatsu; János Ludwig; Drew Weissman
Journal:  Nucleic Acids Res       Date:  2011-09-02       Impact factor: 16.971

10.  Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals.

Authors:  Andreas Thess; Stefanie Grund; Barbara L Mui; Michael J Hope; Patrick Baumhof; Mariola Fotin-Mleczek; Thomas Schlake
Journal:  Mol Ther       Date:  2015-06-08       Impact factor: 11.454
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  29 in total

1.  Modified mRNAs in the Cardiovascular System: A New Platform for Gene Therapy.

Authors:  Georges E Haddad
Journal:  Mol Ther       Date:  2017-05-24       Impact factor: 11.454

2.  Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.

Authors:  Oscar A Marcos-Contreras; Colin F Greineder; Raisa Yu Kiseleva; Hamideh Parhiz; Landis R Walsh; Viviana Zuluaga-Ramirez; Jacob W Myerson; Elizabeth D Hood; Carlos H Villa; Istvan Tombacz; Norbert Pardi; Alecia Seliga; Barbara L Mui; Ying K Tam; Patrick M Glassman; Vladimir V Shuvaev; Jia Nong; Jacob S Brenner; Makan Khoshnejad; Tom Madden; Drew Weissmann; Yuri Persidsky; Vladimir R Muzykantov
Journal:  Proc Natl Acad Sci U S A       Date:  2020-01-31       Impact factor: 11.205

Review 3.  Vaccines to prevent genital herpes.

Authors:  Kevin Egan; Lauren M Hook; Philip LaTourette; Angela Desmond; Sita Awasthi; Harvey M Friedman
Journal:  Transl Res       Date:  2020-03-16       Impact factor: 7.012

Review 4.  Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications.

Authors:  Siddharth Patel; Avathamsa Athirasala; Paula P Menezes; N Ashwanikumar; Ting Zou; Gaurav Sahay; Luiz E Bertassoni
Journal:  Tissue Eng Part A       Date:  2018-06-07       Impact factor: 3.845

5.  Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo.

Authors:  Yizhou Dong; J Robert Dorkin; Weiheng Wang; Philip H Chang; Matthew J Webber; Benjamin C Tang; Junghoon Yang; Inbal Abutbul-Ionita; Dganit Danino; Frank DeRosa; Michael Heartlein; Robert Langer; Daniel G Anderson
Journal:  Nano Lett       Date:  2016-01-13       Impact factor: 11.189

Review 6.  Tapping the RNA world for therapeutics.

Authors:  Judy Lieberman
Journal:  Nat Struct Mol Biol       Date:  2018-04-16       Impact factor: 15.369

Review 7.  The legacy of mRNA engineering: A lineup of pioneers for the Nobel Prize.

Authors:  Miroslaw Janowski; Anna Andrzejewska
Journal:  Mol Ther Nucleic Acids       Date:  2022-07-13       Impact factor: 10.183

8.  RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges.

Authors:  Ai-Ming Yu; Young Hee Choi; Mei-Juan Tu
Journal:  Pharmacol Rev       Date:  2020-10       Impact factor: 25.468

9.  Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo.

Authors:  Kevin J Kauffman; Faryal F Mir; Siddharth Jhunjhunwala; James C Kaczmarek; Juan E Hurtado; Jung H Yang; Matthew J Webber; Piotr S Kowalski; Michael W Heartlein; Frank DeRosa; Daniel G Anderson
Journal:  Biomaterials       Date:  2016-09-25       Impact factor: 12.479

10.  Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening.

Authors:  Pedro P G Guimaraes; Rui Zhang; Roman Spektor; Mingchee Tan; Amanda Chung; Margaret M Billingsley; Rakan El-Mayta; Rachel S Riley; Lili Wang; James M Wilson; Michael J Mitchell
Journal:  J Control Release       Date:  2019-10-31       Impact factor: 9.776
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