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Literature DB >> 26321057

Urothelial carcinoma with squamous differentiation--the pathologists׳ perspective.

Lan L Gellert¹, Joshua Warrick², Hikmat A Al-Ahmadie³.

Abstract

Squamous differentiation is the most common variant histology in urothelial carcinoma and may have effects on clinical outcome. Inconsistencies in reporting variant histologies in urothelial carcinoma are well documented. Immunohistochemical and molecular markers may help identify tumors with squamous differentiation beyond light microscopy.

Entities: Disease

Keywords: Molecular subtypes; Squamous cell carcinoma; Squamous differentiation; Urothelial carcinoma; Variant histology

Mesh：

Substances：
Biomarkers, Tumor

Year: 2015 PMID： 26321057 DOI： 10.1016/j.urolonc.2015.07.018

Source DB: PubMed Journal: Urol Oncol ISSN： 1078-1439 Impact factor: 3.498

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Cited

8 in total

1. Elevated connexin 43 expression in arsenite-and cadmium-transformed human bladder cancer cells, tumor transplants and selected high grade human bladder cancers.

Authors: Ruowen Zhang; Liping Wang; Scott H Garrett; Donald A Sens; Jane R Dunlevy; Xu Dong Zhou; Seema Somji
Journal: Exp Toxicol Pathol Date: 2016-08-13

2. Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer.

Authors: Suk Hyung Lee; Wenhuo Hu; Justin T Matulay; Mark V Silva; Tomasz B Owczarek; Kwanghee Kim; Chee Wai Chua; LaMont J Barlow; Cyriac Kandoth; Alanna B Williams; Sarah K Bergren; Eugene J Pietzak; Christopher B Anderson; Mitchell C Benson; Jonathan A Coleman; Barry S Taylor; Cory Abate-Shen; James M McKiernan; Hikmat Al-Ahmadie; David B Solit; Michael M Shen
Journal: Cell Date: 2018-04-05 Impact factor: 41.582

3. Activation of PPARγ and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As3+-transformed UROtsa cells.

Authors: Aaron A Mehus; Nicholas Bergum; Peter Knutson; Swojani Shrestha; Xu Dong Zhou; Scott H Garrett; Donald A Sens; Mary Ann Sens; Seema Somji
Journal: PLoS One Date: 2020-08-21 Impact factor: 3.240

Urothelial carcinoma with squamous differentiation--the pathologists׳ perspective.

1. Elevated connexin 43 expression in arsenite-and cadmium-transformed human bladder cancer cells, tumor transplants and selected high grade human bladder cancers.

2. Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer.

3. Activation of PPARγ and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As3+-transformed UROtsa cells.

4. Clinical Significance of Squamous Differentiation in Urothelial Carcinoma of the Bladder.

5. BCG instillation versus radical cystectomy for high-risk NMIBC with squamous/glandular histologic variants.

6. Fluorescence-Based Microendoscopic Sensing System for Minimally Invasive In Vivo Bladder Cancer Diagnosis.

7. Primary urethral carcinoma with variant histology: A case report and literature review.

8. Reduced Expression Level of GPX2 in T1 Bladder Cancer and its Role in Early-phase Invasion of Bladder Cancer.