| Literature DB >> 26320157 |
Abstract
Platelets have an emerging and incompletely understood role in a myriad of host immune responses, extending their role well beyond regulating thrombosis. Acute respiratory distress syndrome is a complex disease process characterized by a range of pathophysiologic processes including oxidative stress, lung deformation, inflammation, and intravascular coagulation. The objective of this review is to summarize existing knowledge on platelets and their putative role in the development and resolution of lung injury.Entities:
Keywords: ALI; ARDS; aspirin; lung injury; platelet
Mesh:
Year: 2015 PMID: 26320157 PMCID: PMC4628982 DOI: 10.1152/ajplung.00266.2015
Source DB: PubMed Journal: Am J Physiol Lung Cell Mol Physiol ISSN: 1040-0605 Impact factor: 5.464