Primary Care of the Patient with Chronic Kidney Disease.

Chronic kidney disease (CKD) is defined by reduced estimated glomerular filtration rate, increased proteinuria, or both. CKD affects more than 10% of US adults, or 20 million people, and the numbers are rising as the population ages. However, CKD remains underdiagnosed. Diabetes and hypertension are the most common causes of CKD. Although end-stage renal disease is a feared complication of CKD, patients with CKD have a much greater risk of dying of cardiovascular (CV) disease than progressing to kidney failure. Special effort should be made to address modifiable CV risk factors in patients with CKD.