Literature DB >> 26319820

[LOW-FAT, FERMENTED MILK ENRICHED WITH PLANT STEROLS, A STRATEGY TO REDUCE HYPERTRIGLYCERIDEMA IN CHILDREN, A DOUBLE-BLIND, RANDOMIZED PLACEBO-COTROLLED TRIAL].

Javier Andrés Blumenfeld Olivares1, Ismael San Mauro Martín2, Maria Elisa Calle2, Cornelia Bischofberger Valdés1, Eva Perez Arruche1, Esperanza Arce Delgado1, María Jose Ciudad2, Marta Hernández Cabría3, Luis Collado Yurita2.   

Abstract

INTRODUCTION: in the last few years, as the rate of childhood obesity has been rising, there has been a parallel increase in the incidence of dislipemia in the pediatric population, in which blood triglycerids might play an important role. Plant sterols have been shown to be useful in the tratment of hypercholesterolemia, but not of hypertrygliceridemia. Our study focusses on determining the efficacy of phytosterol-supplemented milk for the treatment of hypertriglyceridemia in children. Study Population and Method: we designed a double- blind, randomized, controlled clinical trial on 67 pediatric patients. The treatment group received low-fat, phytosterol-supplemented milk and the control group received low-fat conventional milk.
RESULTS: we observed differences in triglyceridemia between the phytosterol-supplemented group and the non-supplemented group. The effect attributable to the intake of milk supplemented with plant sterols was a reduction of triglyceridemia of 5.88 mg/dl compared with the control group.
CONCLUSION: we conclude that phytosterol-supplemented milk (2.24 gr of plant sterols daily) might be an adequate tool in the management of hypertriglyceridemia in pediatric patients. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

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Year:  2015        PMID: 26319820     DOI: 10.3305/nh.2015.32.3.9319

Source DB:  PubMed          Journal:  Nutr Hosp        ISSN: 0212-1611            Impact factor:   1.057


  2 in total

1.  Oxidative status of a yogurt-like fermented maize product containing phytosterols.

Authors:  Adriana María Descalzo; Sergio Aníbal Rizzo; Adrien Servent; Luciana Rossetti; Marc Lebrun; Carolina Daiana Pérez; Renaud Boulanger; Christian Mestres; Dominique Pallet; Claudie Dhuique-Mayer
Journal:  J Food Sci Technol       Date:  2018-03-19       Impact factor: 2.701

Review 2.  The Lipid-lowering Effects and Associated Mechanisms of Dietary Phytosterol Supplementation.

Authors:  Jerad H Dumolt; Todd C Rideout
Journal:  Curr Pharm Des       Date:  2017       Impact factor: 3.116

  2 in total

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