Ana Santiago1, Carlos Carpio1, Paloma Caballero2, Antonio Martín-Duce3, Gregorio Vesperinas4, Francisco Gómez de Terreros5, M A Gómez Mendieta1, Rodolfo Álvarez-Sala1, Abelardo García de Lorenzo6. 1. Servicio de Neumología. Hospital Universitario La Paz. IdiPAZ. Departamento de Medicina y Cirugía. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com. 2. Servicio de Radiología. Hospital Universitario de La Princesa. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com. 3. Servicio de Cirugía General. Hospital Universitario Príncipe de Asturias. Departamento de Cirugía. Universidad Alcalá de Henares.. carlinjavier@hotmail.com. 4. Servicio de Cirugía General. Hospital Universitario La Paz, Madrid.. carlinjavier@hotmail.com. 5. Servicio de Neumología. Hospital San Pedro Alcántara, Cáceres.. carlinjavier@hotmail.com. 6. Servicio de Medicina Intensiva. Hospital Universitario La Paz. IdiPAZ. Universidad Autónoma de Madrid, España.. carlinjavier@hotmail.com.
Abstract
INTRODUCTION: obesity impacts on respiratory function and also it acts as a risk factor for obstructive sleep apnea (OSA). AIMS: to study the effects of bariatric surgery on pulmonary function tests and on OSA in morbidly obese women over 4 years. METHODS: fifteen morbidly obese women (mean body mass index [BMI] 50.52 ± 12.71 kg.m-2, mean age 40.13 ± 10.06 years) underwent pulmonary function tests (PFT) in two opportunities (before and after weight loss surgery). PFT included spirometry, body plethysmography and measure of maximal inspiratory mouth pressure (PImax) and of tension-time index for inspiratory muscles. Also, in both opportunities, resting arterial blood gas tensions were evaluated and a full night sleep register was performed. RESULTS: BMI significantly decreased after bariatric surgery (-44.07 kg.m-2 [CI 95% -38.32 - -49.81]). Also, there was a significantly increase in forced expiratory volume in 1 second (FEV1) (p < 0.01), forced vital capacity (FVC) (p < 0.01), expiratory reserve volume (ERV) (p = 0.040), functional residual capacity (FRC) (p = 0.009) and a decline in airways resistance (Raw) (p = 0.018). Concerning sleep registers, apnea hypopnea index (p = 0.001) and desaturation index (p = 0.001) were also reduced after weight loss. Improve in ERV had a significant correlation with weight loss (r = 0.774, p = 0.024). Conclussions: pulmonary function tests and apnea hypopnea index improve after bariatric surgery in mor bidly obese women. Improvement of ERV is well correlated with weight loss. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
INTRODUCTION:obesity impacts on respiratory function and also it acts as a risk factor for obstructive sleep apnea (OSA). AIMS: to study the effects of bariatric surgery on pulmonary function tests and on OSA in morbidly obesewomen over 4 years. METHODS: fifteen morbidly obesewomen (mean body mass index [BMI] 50.52 ± 12.71 kg.m-2, mean age 40.13 ± 10.06 years) underwent pulmonary function tests (PFT) in two opportunities (before and after weight loss surgery). PFT included spirometry, body plethysmography and measure of maximal inspiratory mouth pressure (PImax) and of tension-time index for inspiratory muscles. Also, in both opportunities, resting arterial blood gas tensions were evaluated and a full night sleep register was performed. RESULTS: BMI significantly decreased after bariatric surgery (-44.07 kg.m-2 [CI 95% -38.32 - -49.81]). Also, there was a significantly increase in forced expiratory volume in 1 second (FEV1) (p < 0.01), forced vital capacity (FVC) (p < 0.01), expiratory reserve volume (ERV) (p = 0.040), functional residual capacity (FRC) (p = 0.009) and a decline in airways resistance (Raw) (p = 0.018). Concerning sleep registers, apnea hypopnea index (p = 0.001) and desaturation index (p = 0.001) were also reduced after weight loss. Improve in ERV had a significant correlation with weight loss (r = 0.774, p = 0.024). Conclussions: pulmonary function tests and apnea hypopnea index improve after bariatric surgery in mor bidly obesewomen. Improvement of ERV is well correlated with weight loss. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
Authors: Larissa Perossi; Mayara Holtz; Daniele Oliveira Dos Santos; Jéssica Perossi; Hugo Celso Dutra de Souza; Wilson Salgado Junior; Ada Clarice Gastaldi Journal: PLoS One Date: 2022-06-07 Impact factor: 3.752