Literature DB >> 26316239

Menopausal Symptoms and Their Management.

Nanette Santoro1, C Neill Epperson2, Sarah B Mathews2.   

Abstract

The menopause transition is associated with various symptoms, which can interact to produce morbidity. Vasomotor symptoms are the most commonly reported, but vaginal dryness/dyspareunia, sleep difficulties and adverse mood changes have all been shown to worsen as women approach menopause. For postmenopausal women changes in cognition are more likely to be related to aging and not to hormones. This article reviews the symptoms of hot flashes (vasomotor symptoms), vaginal dryness/dyspareunia, adverse mood, poor sleep/insomnia, and cognitive complaints, describing their epidemiology, diagnosis, and treatment. This article thus reviews the epidemiology, pathophysiology, diagnosis, and treatment of these common menopausal symptoms.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cognitive impairment; Depression; Dyspareunia; Insomnia; Menopause; Perimenopause; Vaginal dryness; Vasomotor symptoms

Mesh:

Year:  2015        PMID: 26316239      PMCID: PMC4890704          DOI: 10.1016/j.ecl.2015.05.001

Source DB:  PubMed          Journal:  Endocrinol Metab Clin North Am        ISSN: 0889-8529            Impact factor:   4.741


  53 in total

1.  Health care-seeking for menopausal problems.

Authors:  J R Guthrie; L Dennerstein; J R Taffe; V Donnelly
Journal:  Climacteric       Date:  2003-06       Impact factor: 3.005

2.  Longitudinal analysis of the association between vasomotor symptoms and race/ethnicity across the menopausal transition: study of women's health across the nation.

Authors:  Ellen B Gold; Alicia Colvin; Nancy Avis; Joyce Bromberger; Gail A Greendale; Lynda Powell; Barbara Sternfeld; Karen Matthews
Journal:  Am J Public Health       Date:  2006-05-30       Impact factor: 9.308

3.  Double-blind, placebo-controlled psychometric studies on the effects of a combined estrogen-progestin regimen versus estrogen alone on performance, mood and personality of menopausal syndrome patients.

Authors:  L Linzmayer; H V Semlitsch; B Saletu; G Böck; G Saletu-Zyhlarz; A Zoghlami; D Gruber; M Metka; J Huber; M Oettel; T Gräser; J Grünberger
Journal:  Arzneimittelforschung       Date:  2001

Review 4.  Effect of estrogen-serotonin interactions on mood and cognition.

Authors:  Zenab Amin; Turhan Canli; C Neill Epperson
Journal:  Behav Cogn Neurosci Rev       Date:  2005-03

5.  Impact of atomoxetine on subjective attention and memory difficulties in perimenopausal and postmenopausal women.

Authors:  C Neill Epperson; Brian Pittman; Kathryn A Czarkowski; Jeanette Bradley; Donald M Quinlan; Thomas E Brown
Journal:  Menopause       Date:  2011-05       Impact factor: 2.953

6.  Memory functioning among midlife women: observations from the Seattle Midlife Women's Health Study.

Authors:  N F Woods; E S Mitchell; C Adams
Journal:  Menopause       Date:  2000 Jul-Aug       Impact factor: 2.953

7.  Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women: a double-blind, randomized, placebo-controlled trial.

Authors:  C N Soares; O P Almeida; H Joffe; L S Cohen
Journal:  Arch Gen Psychiatry       Date:  2001-06

8.  A one-year multicenter study of efficacy and safety of a continuous, low-dose, estradiol-releasing vaginal ring (Estring) in postmenopausal women with symptoms and signs of urogenital aging.

Authors:  L Henriksson; M Stjernquist; L Boquist; I Cedergren; I Selinus
Journal:  Am J Obstet Gynecol       Date:  1996-01       Impact factor: 8.661

9.  Lack of efficacy of estradiol for depression in postmenopausal women: a randomized, controlled trial.

Authors:  Mary F Morrison; Michael J Kallan; Thomas Ten Have; Ira Katz; Kathryn Tweedy; Michelle Battistini
Journal:  Biol Psychiatry       Date:  2004-02-15       Impact factor: 13.382

10.  Variations in memory function and sex steroid hormones across the menstrual cycle.

Authors:  S M Phillips; B B Sherwin
Journal:  Psychoneuroendocrinology       Date:  1992-10       Impact factor: 4.905

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  66 in total

Review 1.  Depression During and After the Perimenopause: Impact of Hormones, Genetics, and Environmental Determinants of Disease.

Authors:  Joyce T Bromberger; Cynthia Neill Epperson
Journal:  Obstet Gynecol Clin North Am       Date:  2018-10-25       Impact factor: 2.844

2.  Encapsulation of Mesenchymal Stem Cells in 3D Ovarian Cell Constructs Promotes Stable and Long-Term Hormone Secretion with Improved Physiological Outcomes in a Syngeneic Rat Model.

Authors:  Sivanandane Sittadjody; Kevin M Enck; Alexandra Wells; James J Yoo; Anthony Atala; Justin M Saul; Emmanuel C Opara
Journal:  Ann Biomed Eng       Date:  2019-07-31       Impact factor: 3.934

3.  Sleep Disorders in Postmenopausal Women.

Authors:  Shazia Jehan; Alina Masters-Isarilov; Idoko Salifu; Ferdinand Zizi; Girardin Jean-Louis; Seithikurippu R Pandi-Perumal; Ravi Gupta; Amnon Brzezinski; Samy I McFarlane
Journal:  J Sleep Disord Ther       Date:  2015-08-25

4.  Efficacy and patient satisfaction of pelvic organ prolapse reduction using transvaginal mesh: A Canadian perspective.

Authors:  Mélanie Aubé; Marilyne Guérin; Caroline Rheaume; Le Mai Tu
Journal:  Can Urol Assoc J       Date:  2018-05-28       Impact factor: 1.862

5.  Ojayeonjonghwan, an oriental medicine composed of five seeds, protects against vasomotor and neurological disorders in estrogen-deficient rats.

Authors:  Byoung-Seob Ko; Jin Ah Ryuk; Joo Tae Hwang; Ting Zhang; Xuangao Wu; Sunmin Park
Journal:  Exp Biol Med (Maywood)       Date:  2019-02-05

6.  Effect of the Fractional CO2 Laser on the Quality of Life, General Health, and Genitourinary Symptoms in Postmenopausal Women With Vaginal Atrophy: A Prospective Cohort.

Authors:  Khadijeh Adabi; Fatemeh Golshahi; Shirin Niroomansh; Zahra Razzaghi; Marjan Ghaemi
Journal:  J Lasers Med Sci       Date:  2020-01-18

Review 7.  Uterine fibroids in menopause and perimenopause.

Authors:  Mara Ulin; Mohamed Ali; Zunir Tayyeb Chaudhry; Ayman Al-Hendy; Qiwei Yang
Journal:  Menopause       Date:  2020-02       Impact factor: 2.953

Review 8.  What has sex got to do with it? The role of hormones in the transgender brain.

Authors:  Hillary B Nguyen; James Loughead; Emily Lipner; Liisa Hantsoo; Sara L Kornfield; C Neill Epperson
Journal:  Neuropsychopharmacology       Date:  2018-07-05       Impact factor: 7.853

9.  Double-Blind Controlled Trial of Vitamin E Effects on Serum Lipid Profile in Menopausal Women.

Authors:  Parvaneh Rezasoltani; Nahid Elliyoun; Tahereh Ziaie; Abdolrasoul Sobhani; Ehsan Kazemnezhjad Leyli; Soudabeh Kazemi Aski
Journal:  Diabetes Metab Syndr Obes       Date:  2021-03-09       Impact factor: 3.168

Review 10.  Assessment of the climacteric syndrome: a narrative review.

Authors:  Marina Sourouni; Martina Zangger; Livia Honermann; Dolores Foth; Petra Stute
Journal:  Arch Gynecol Obstet       Date:  2021-07-06       Impact factor: 2.344

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