| Literature DB >> 26315872 |
Angelina Cistaro1, Natale Quartuccio, Federico Caobelli, Arnoldo Piccardo, Rosario Paratore, Pietro Coppolino, Alessandro Sperandeo, Gaspare Arnone, Umberto Ficola.
Abstract
Neuroblastoma is the most common extra-cranial solid tumor in pediatric patients. Despite the established role of 123I-MIBG and 131I-MIBG scintigraphy in this tumor, only limited data are available regarding the use of 124I-metaiodobenzylguanidine (MIBG) positron emission tomography (PET)/computed tomography (CT). We present our preliminary experience with 124I-MIBG PET/CT: two pediatric patients affected by neuroblastoma, who underwent 124I-MIBG PET/CT for pre-therapy distribution evaluation and restaging purposes. We aimed to evaluate whether 124I-MIBG PET/CT can detect as many or more neuroblastoma lesions than 123I/131I-MIBG imaging. Our cases show promising results, although further validation and standardization of 124I-MIBG PET/CT are required.Entities:
Mesh:
Substances:
Year: 2015 PMID: 26315872 DOI: 10.5603/NMR.2015.0024
Source DB: PubMed Journal: Nucl Med Rev Cent East Eur ISSN: 1506-9680