Literature DB >> 26315817

Nano-enabled delivery of diverse payloads across complex biological barriers.

Kathleen A Ross1, Timothy M Brenza1, Andrea M Binnebose2, Yashdeep Phanse3, Anumantha G Kanthasamy4, Howard E Gendelman5, Aliasger K Salem6, Lyric C Bartholomay3, Bryan H Bellaire2, Balaji Narasimhan7.   

Abstract

Complex biological barriers are major obstacles for preventing and treating disease. Nanocarriers are designed to overcome such obstacles by enhancing drug delivery through physiochemical barriers and improving therapeutic indices. This review critically examines both biological barriers and nanocarrier payloads for a variety of drug delivery applications. A spectrum of nanocarriers is discussed that have been successfully developed for improving tissue penetration for preventing or treating a range of infectious, inflammatory, and degenerative diseases.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biological barriers; Blood–brain barrier; Drug delivery; Nanoparticle; Tumor microenvironment; Vector-borne disease

Mesh:

Substances:

Year:  2015        PMID: 26315817      PMCID: PMC4656048          DOI: 10.1016/j.jconrel.2015.08.039

Source DB:  PubMed          Journal:  J Control Release        ISSN: 0168-3659            Impact factor:   9.776


  175 in total

Review 1.  Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

Authors:  David J Begley
Journal:  Pharmacol Ther       Date:  2004-10       Impact factor: 12.310

2.  Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease.

Authors:  Maarten Rotman; Mick M Welling; Anton Bunschoten; Maaike E de Backer; Jaap Rip; Rob J A Nabuurs; Pieter J Gaillard; Mark A van Buchem; Silvère M van der Maarel; Louise van der Weerd
Journal:  J Control Release       Date:  2015-02-07       Impact factor: 9.776

3.  Influence of cholesterol on liposome stability and on in vitro drug release.

Authors:  Maria-Lucia Briuglia; Chiara Rotella; Amber McFarlane; Dimitrios A Lamprou
Journal:  Drug Deliv Transl Res       Date:  2015-06       Impact factor: 4.617

Review 4.  Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery.

Authors:  Julien Nicolas; Simona Mura; Davide Brambilla; Nicolas Mackiewicz; Patrick Couvreur
Journal:  Chem Soc Rev       Date:  2013-02-07       Impact factor: 54.564

5.  Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier.

Authors:  Jörg Kreuter; Dmitry Shamenkov; Valery Petrov; Peter Ramge; Klaus Cychutek; Claudia Koch-Brandt; Renad Alyautdin
Journal:  J Drug Target       Date:  2002-06       Impact factor: 5.121

6.  Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection.

Authors:  Muge Yemisci; Secil Caban; Yasemin Gursoy-Ozdemir; Sevda Lule; Ramon Novoa-Carballal; Ricardo Riguera; Eduardo Fernandez-Megia; Karine Andrieux; Partick Couvreur; Yilmaz Capan; Turgay Dalkara
Journal:  J Cereb Blood Flow Metab       Date:  2014-12-10       Impact factor: 6.200

7.  Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface.

Authors:  Anna Salvati; Andrzej S Pitek; Marco P Monopoli; Kanlaya Prapainop; Francesca Baldelli Bombelli; Delyan R Hristov; Philip M Kelly; Christoffer Åberg; Eugene Mahon; Kenneth A Dawson
Journal:  Nat Nanotechnol       Date:  2013-01-20       Impact factor: 39.213

8.  Design of a protective single-dose intranasal nanoparticle-based vaccine platform for respiratory infectious diseases.

Authors:  Bret D Ulery; Devender Kumar; Amanda E Ramer-Tait; Dennis W Metzger; Michael J Wannemuehler; Balaji Narasimhan
Journal:  PLoS One       Date:  2011-03-03       Impact factor: 3.240

9.  Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.

Authors:  Andrea M Binnebose; Shannon L Haughney; Richard Martin; Paula M Imerman; Balaji Narasimhan; Bryan H Bellaire
Journal:  PLoS Negl Trop Dis       Date:  2015-10-23

Review 10.  Enzymology of the nematode cuticle: A potential drug target?

Authors:  Antony P Page; Gillian Stepek; Alan D Winter; David Pertab
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2014-06-06       Impact factor: 4.077

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  13 in total

1.  In vitro Pharmacokinetic Cell Culture System that Simulates Physiologic Drug and Nanoparticle Exposure to Macrophages.

Authors:  Hilliard L Kutscher; Gene D Morse; Paras N Prasad; Jessica L Reynolds
Journal:  Pharm Res       Date:  2019-02-01       Impact factor: 4.200

2.  Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy.

Authors:  Timothy M Brenza; Shivani Ghaisas; Julia E Vela Ramirez; Dilshan Harischandra; Vellareddy Anantharam; Balaraman Kalyanaraman; Anumantha G Kanthasamy; Balaji Narasimhan
Journal:  Nanomedicine       Date:  2016-10-19       Impact factor: 5.307

3.  Biodegradable polyanhydride-based nanomedicines for blood to brain drug delivery.

Authors:  Timothy M Brenza; Benjamin W Schlichtmann; Biju Bhargavan; Julia E Vela Ramirez; Rainie D Nelson; Matthew G Panthani; JoEllyn M McMillan; Balaraman Kalyanaraman; Howard E Gendelman; Vellareddy Anantharam; Anumantha G Kanthasamy; Surya K Mallapragada; Balaji Narasimhan; Georgette D Kanmogne
Journal:  J Biomed Mater Res A       Date:  2018-10-26       Impact factor: 4.396

Review 4.  Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior.

Authors:  Miles A Miller; Ralph Weissleder
Journal:  Adv Drug Deliv Rev       Date:  2016-06-04       Impact factor: 15.470

5.  Mathematical Modeling and Experimental Validation of Nanoemulsion-Based Drug Transport across Cellular Barriers.

Authors:  Ekta Kadakia; Lipa Shah; Mansoor M Amiji
Journal:  Pharm Res       Date:  2017-04-07       Impact factor: 4.200

6.  Macrophage Targeted Nanoparticles for Antiretroviral (ARV) Delivery.

Authors:  Hilliard L Kutscher; Faithful Makita-Chingombe; Sara DiTursi; Ajay Singh; Admire Dube; Charles C Maponga; Gene D Morse; Jessica L Reynolds
Journal:  J Pers Nanomed       Date:  2015-11-14

7.  Analytical ultracentrifugation for analysis of doxorubicin loaded liposomes.

Authors:  Dora Mehn; Patrizia Iavicoli; Noelia Cabaleiro; Sven Even Borgos; Fanny Caputo; Otmar Geiss; Luigi Calzolai; François Rossi; Douglas Gilliland
Journal:  Int J Pharm       Date:  2017-03-22       Impact factor: 5.875

Review 8.  Nanobased Platforms for Diagnosis and Treatment of COVID-19: From Benchtop to Bedside.

Authors:  Elham Bidram; Yasaman Esmaeili; Abbas Amini; Rossella Sartorius; Franklin R Tay; Laleh Shariati; Pooyan Makvandi
Journal:  ACS Biomater Sci Eng       Date:  2021-05-12

Review 9.  Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies.

Authors:  Luman Liu; Prakash G Kshirsagar; Shailendra K Gautam; Mansi Gulati; Emad I Wafa; John C Christiansen; Brianna M White; Surya K Mallapragada; Michael J Wannemuehler; Sushil Kumar; Joyce C Solheim; Surinder K Batra; Aliasger K Salem; Balaji Narasimhan; Maneesh Jain
Journal:  Theranostics       Date:  2022-01-01       Impact factor: 11.600

10.  Bovine NK-lysin peptides exert potent antimicrobial activity against multidrug-resistant Salmonella outbreak isolates.

Authors:  Rohana P Dassanayake; Briony M Atkinson; Adam S Mullis; Shollie M Falkenberg; Eric M Nicholson; Eduardo Casas; Balaji Narasimhan; Shawn M D Bearson
Journal:  Sci Rep       Date:  2021-09-29       Impact factor: 4.996

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