Literature DB >> 26315636

Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly.

Miles Berger1, Jacob W Nadler2, Jeffrey Browndyke2, Niccolo Terrando2, Vikram Ponnusamy2, Harvey Jay Cohen2, Heather E Whitson2, Joseph P Mathew2.   

Abstract

Postoperative cognitive dysfunction (POCD) is a common complication associated with significant morbidity and mortality in elderly patients. There is much interest in and controversy about POCD, reflected partly in the increasing number of articles published on POCD recently. Recent work suggests surgery may also be associated with cognitive improvement in some patients, termed postoperative cognitive improvement (POCI). As the number of surgeries performed worldwide approaches 250 million per year, optimizing postoperative cognitive function and preventing/treating POCD are major public health issues. In this article, we review the literature on POCD and POCI, and discuss current research challenges in this area.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Anesthesia; Elderly; Post-operative cognitive decline; Post-operative cognitive dysfunction; Post-operative cognitive improvement; Surgery

Mesh:

Year:  2015        PMID: 26315636      PMCID: PMC4555995          DOI: 10.1016/j.anclin.2015.05.008

Source DB:  PubMed          Journal:  Anesthesiol Clin        ISSN: 1932-2275


  164 in total

1.  Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery.

Authors:  Barbara Phillips-Bute; Joseph P Mathew; James A Blumenthal; Hilary P Grocott; Daniel T Laskowitz; Robert H Jones; Daniel B Mark; Mark F Newman
Journal:  Psychosom Med       Date:  2006 May-Jun       Impact factor: 4.312

2.  Effects of exercise training on frailty in community-dwelling older adults: results of a randomized, controlled trial.

Authors:  Ellen F Binder; Kenneth B Schechtman; Ali A Ehsani; Karen Steger-May; Marybeth Brown; David R Sinacore; Kevin E Yarasheski; John O Holloszy
Journal:  J Am Geriatr Soc       Date:  2002-12       Impact factor: 5.562

3.  Remote ischemic preconditioning prevents deterioration of short-term postoperative cognitive function after cardiac surgery using cardiopulmonary bypass: results of a pilot investigation.

Authors:  Judith A Hudetz; Kathleen M Patterson; Zafar Iqbal; Sweeta D Gandhi; Paul S Pagel
Journal:  J Cardiothorac Vasc Anesth       Date:  2014-11-01       Impact factor: 2.628

4.  Preliminary report of the effects of complement suppression with pexelizumab on neurocognitive decline after coronary artery bypass graft surgery.

Authors:  Joseph P Mathew; Stanton K Shernan; William D White; Jane C K Fitch; John C Chen; Leonard Bell; Mark F Newman
Journal:  Stroke       Date:  2004-08-26       Impact factor: 7.914

5.  Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness.

Authors:  Michael S Avidan; Adam C Searleman; Martha Storandt; Kara Barnett; Andrea Vannucci; Leif Saager; Chengjie Xiong; Elizabeth A Grant; Dagmar Kaiser; John C Morris; Alex S Evers
Journal:  Anesthesiology       Date:  2009-11       Impact factor: 7.892

Review 6.  Cerebral near-infrared spectroscopy monitoring and neurologic outcomes in adult cardiac surgery patients: a systematic review.

Authors:  Fei Zheng; Rosanne Sheinberg; May-Sann Yee; Masa Ono; Yueyging Zheng; Charles W Hogue
Journal:  Anesth Analg       Date:  2012-12-24       Impact factor: 5.108

7.  Prehabilitation versus rehabilitation: a randomized control trial in patients undergoing colorectal resection for cancer.

Authors:  Chelsia Gillis; Chao Li; Lawrence Lee; Rashami Awasthi; Berson Augustin; Ann Gamsa; A Sender Liberman; Barry Stein; Patrick Charlebois; Liane S Feldman; Francesco Carli
Journal:  Anesthesiology       Date:  2014-11       Impact factor: 7.892

8.  Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial.

Authors:  William J Mack; Christopher P Kellner; Daniel H Sahlein; Andrew F Ducruet; Grace H Kim; J Mocco; Joseph Zurica; Ricardo J Komotar; Raqeeb Haque; Robert Sciacca; Donald O Quest; Robert A Solomon; E Sander Connolly; Eric J Heyer
Journal:  J Neurosurg       Date:  2009-05       Impact factor: 5.115

9.  Resolving postoperative neuroinflammation and cognitive decline.

Authors:  Niccolò Terrando; Lars I Eriksson; Jae Kyu Ryu; Ting Yang; Claudia Monaco; Marc Feldmann; Malin Jonsson Fagerlund; Israel F Charo; Katerina Akassoglou; Mervyn Maze
Journal:  Ann Neurol       Date:  2011-12       Impact factor: 10.422

10.  General anaesthesia does not contribute to long-term post-operative cognitive dysfunction in adults: A meta-analysis.

Authors:  Joanne Guay
Journal:  Indian J Anaesth       Date:  2011-07
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  74 in total

1.  Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence.

Authors:  Lori A Daiello; Annie M Racine; Ray Yun Gou; Edward R Marcantonio; Zhongcong Xie; Lisa J Kunze; Kamen V Vlassakov; Sharon K Inouye; Richard N Jones; David Alsop; Thomas Travison; Steven Arnold; Zara Cooper; Bradford Dickerson; Tamara Fong; Eran Metzger; Alvaro Pascual-Leone; Eva M Schmitt; Mouhsin Shafi; Michele Cavallari; Weiying Dai; Simon T Dillon; Janet McElhaney; Charles Guttmann; Tammy Hshieh; George Kuchel; Towia Libermann; Long Ngo; Daniel Press; Jane Saczynski; Sarinnapha Vasunilashorn; Margaret O'Connor; Eyal Kimchi; Jason Strauss; Bonnie Wong; Michael Belkin; Douglas Ayres; Mark Callery; Frank Pomposelli; John Wright; Marc Schermerhorn; Tatiana Abrantes; Asha Albuquerque; Sylvie Bertrand; Amanda Brown; Amy Callahan; Madeline D'Aquila; Sarah Dowal; Meaghan Fox; Jacqueline Gallagher; Rebecca Anna Gersten; Ariel Hodara; Ben Helfand; Jennifer Inloes; Jennifer Kettell; Aleksandra Kuczmarska; Jacqueline Nee; Emese Nemeth; Lisa Ochsner; Kerry Palihnich; Katelyn Parisi; Margaret Puelle; Sarah Rastegar; Margaret Vella; Guoquan Xu; Margaret Bryan; Jamey Guess; Dee Enghorn; Alden Gross; Yun Gou; Daniel Habtemariam; Ilean Isaza; Cyrus Kosar; Christopher Rockett; Douglas Tommet; Ted Gruen; Meg Ross; Katherine Tasker; James Gee; Ann Kolanowski; Margaret Pisani; Sophia de Rooij; Selwyn Rogers; Stephanie Studenski; Yaakov Stern; Anthony Whittemore; Gary Gottlieb; John Orav; Reisa Sperling
Journal:  Anesthesiology       Date:  2019-09       Impact factor: 7.892

Review 2.  Lasting impact of general anaesthesia on the brain: mechanisms and relevance.

Authors:  Laszlo Vutskits; Zhongcong Xie
Journal:  Nat Rev Neurosci       Date:  2016-10-18       Impact factor: 34.870

3.  Proposed Standardized Neurological Endpoints for Cardiovascular Clinical Trials: An Academic Research Consortium Initiative.

Authors:  Alexandra J Lansky; Steven R Messé; Adam M Brickman; Michael Dwyer; H Bart van der Worp; Ronald M Lazar; Cody G Pietras; Kevin J Abrams; Eugene McFadden; Nils H Petersen; Jeffrey Browndyke; Bernard Prendergast; Vivian G Ng; Donald E Cutlip; Samir Kapadia; Mitchell W Krucoff; Axel Linke; Claudia Scala Moy; Joachim Schofer; Gerrit-Anne van Es; Renu Virmani; Jeffrey Popma; Michael K Parides; Susheel Kodali; Michel Bilello; Robert Zivadinov; Joseph Akar; Karen L Furie; Daryl Gress; Szilard Voros; Jeffrey Moses; David Greer; John K Forrest; David Holmes; Arie P Kappetein; Michael Mack; Andreas Baumbach
Journal:  Eur Heart J       Date:  2018-05-14       Impact factor: 29.983

4.  The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Authors:  Miles Berger; Deborah Oyeyemi; Mobolaji O Olurinde; Heather E Whitson; Kent J Weinhold; Marty G Woldorff; Lewis A Lipsitz; Eugene Moretti; Charles M Giattino; Kenneth C Roberts; Junhong Zhou; Thomas Bunning; Michael Ferrandino; Randall P Scheri; Mary Cooter; Cliburn Chan; Roberto Cabeza; Jeffrey N Browndyke; David M Murdoch; Michael J Devinney; Leslie M Shaw; Harvey Jay Cohen; Joseph P Mathew
Journal:  J Am Geriatr Soc       Date:  2019-01-23       Impact factor: 5.562

5.  General anesthetic exposure in adolescent rats causes persistent maladaptations in cognitive and affective behaviors and neuroplasticity.

Authors:  Justine D Landin; Magdalena Palac; Jenna M Carter; Yvette Dzumaga; Jessica L Santerre-Anderson; Gina M Fernandez; Lisa M Savage; Elena I Varlinskaya; Linda P Spear; Scott D Moore; H Scott Swartzwelder; Rebekah L Fleming; David F Werner
Journal:  Neuropharmacology       Date:  2019-03-26       Impact factor: 5.250

6.  Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial.

Authors:  Rebecca Y Klinger; Mary Cooter; Miles Berger; Mihai V Podgoreanu; Mark Stafford-Smith; Thomas L Ortel; Ian J Welsby; Jerrold H Levy; Henry M Rinder; Mark F Newman; Joseph P Mathew
Journal:  Can J Anaesth       Date:  2016-07-28       Impact factor: 5.063

7.  Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings.

Authors:  Jeffrey N Browndyke; Miles Berger; Todd B Harshbarger; Patrick J Smith; William White; Tiffany L Bisanar; John H Alexander; Jeffrey G Gaca; Kathleen Welsh-Bohmer; Mark F Newman; Joseph P Mathew
Journal:  J Am Geriatr Soc       Date:  2016-11-17       Impact factor: 5.562

8.  Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults.

Authors:  Jeffrey N Browndyke; Miles Berger; Patrick J Smith; Todd B Harshbarger; Zachary A Monge; Viral Panchal; Tiffany L Bisanar; Donald D Glower; John H Alexander; Roberto Cabeza; Kathleen Welsh-Bohmer; Mark F Newman; Joseph P Mathew
Journal:  Hum Brain Mapp       Date:  2017-11-21       Impact factor: 5.038

Review 9.  Neurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms.

Authors:  Miles Berger; Niccolò Terrando; S Kendall Smith; Jeffrey N Browndyke; Mark F Newman; Joseph P Mathew
Journal:  Anesthesiology       Date:  2018-10       Impact factor: 7.892

Review 10.  Contribution of Baroreceptor Function to Pain Perception and Perioperative Outcomes.

Authors:  Heberto Suarez-Roca; Rebecca Y Klinger; Mihai V Podgoreanu; Ru-Rong Ji; Martin I Sigurdsson; Nathan Waldron; Joseph P Mathew; William Maixner
Journal:  Anesthesiology       Date:  2019-04       Impact factor: 7.892

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