Maria José Bento1, Guilherme Gonçalves2, Ana Aguiar3, Clara Castro4, Vitor Veloso5, Vítor Rodrigues6. 1. Institute of Biomedical Sciences Abel Salazar, University of Porto, Rua de Jorge Viterbo, n° 228, 4050-313 Porto, Portugal; Epidemiology Unit, Portuguese Oncology Institute, Rua Dr. Antonio Bernardino de Almeida, 4200-072 Porto, Portugal. Electronic address: mjbento@icbas.up.pt. 2. Institute of Biomedical Sciences Abel Salazar, University of Porto, Rua de Jorge Viterbo, n° 228, 4050-313 Porto, Portugal. Electronic address: aggoncalves@icbas.up.pt. 3. Portuguese Cancer League - North Branch, Porto Estrada Circunv. 6657, 4200-000 Porto, Portugal. Electronic address: anateresaaguiar@netcabo.pt. 4. Epidemiology Unit, Portuguese Oncology Institute, Rua Dr. Antonio Bernardino de Almeida, 4200-072 Porto, Portugal. Electronic address: clara.castro@ipoporto.min-saude.pt. 5. Portuguese Cancer League - North Branch, Porto Estrada Circunv. 6657, 4200-000 Porto, Portugal. Electronic address: presidente.nrnorte@ligacontracancro.pt. 6. Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal; Portuguese Cancer League - Centre Branch, Coimbra Rua Dr. Antonio Jose Almeida 329, 2°-pt 56, 3000-045 Coimbra, Portugal. Electronic address: vrodrigues@netcabo.pt.
Abstract
OBJECTIVE: To evaluate the first 10 years of operation of the population-based breast cancer screening programme implemented in the Northern Region of Portugal, using selected recommended standard performance indicators. METHODS: Data from women aged 50-69 screened with two-view mammography, biennially, in the period 2000-2009, were included. Main performance indicators were compared with the recommended levels of the European Guidelines. RESULTS: A total of 202,039 screening examinations were performed, 71,731 (35.5%) in the initial screening and 130,308 (64.5%) in the subsequent screening. Coverage rate by examination reached 74.3% of the target population, in the last period evaluated. Recall rates were 8.1% and 2.4% and cancer detection rates were 4.4/1000 and 2.9/1000 respectively, for initial and subsequent screenings. The breast cancer detection rate, expressed as a multiple of the background expected incidence was 3.1 in initial screen and 2.2 in subsequent screen. The incidence of invasive interval cancers met the desirable recommended levels both the first and second years since last screening examination, in the initial and subsequent screenings. Invasive tumours <15mm were 50.4% and 53.8% of the invasive cancers detected in initial and subsequent screenings. Less favourable size, grading and biomarkers expression were found in interval cancers compared to screen-detected cancers. CONCLUSIONS: Breast cancer screening programme in the Northern Region of Portugal was well accepted by the population. Most of the performance indicators were consistent with the desirable levels of the European Guidelines, which indicate an effective screening programme. Future research should verify the consistency of some of these results by using updated information from a larger population.
OBJECTIVE: To evaluate the first 10 years of operation of the population-based breast cancer screening programme implemented in the Northern Region of Portugal, using selected recommended standard performance indicators. METHODS: Data from women aged 50-69 screened with two-view mammography, biennially, in the period 2000-2009, were included. Main performance indicators were compared with the recommended levels of the European Guidelines. RESULTS: A total of 202,039 screening examinations were performed, 71,731 (35.5%) in the initial screening and 130,308 (64.5%) in the subsequent screening. Coverage rate by examination reached 74.3% of the target population, in the last period evaluated. Recall rates were 8.1% and 2.4% and cancer detection rates were 4.4/1000 and 2.9/1000 respectively, for initial and subsequent screenings. The breast cancer detection rate, expressed as a multiple of the background expected incidence was 3.1 in initial screen and 2.2 in subsequent screen. The incidence of invasive interval cancers met the desirable recommended levels both the first and second years since last screening examination, in the initial and subsequent screenings. Invasive tumours <15mm were 50.4% and 53.8% of the invasive cancers detected in initial and subsequent screenings. Less favourable size, grading and biomarkers expression were found in interval cancers compared to screen-detected cancers. CONCLUSIONS:Breast cancer screening programme in the Northern Region of Portugal was well accepted by the population. Most of the performance indicators were consistent with the desirable levels of the European Guidelines, which indicate an effective screening programme. Future research should verify the consistency of some of these results by using updated information from a larger population.
Authors: Gonçalo Forjaz de Lacerda; Scott P Kelly; Joana Bastos; Clara Castro; Alexandra Mayer; Angela B Mariotto; William F Anderson Journal: Cancer Epidemiol Date: 2018-03-13 Impact factor: 2.984
Authors: Inês P Santos; Clara B Martins; Luís A E Batista de Carvalho; Maria P M Marques; Ana L M Batista de Carvalho Journal: Cancers (Basel) Date: 2022-01-17 Impact factor: 6.639