| Literature DB >> 26312673 |
Maria Victória Quaresma1, Fred Bernardes Filho1, Janaína Hezel1, Murilo Calvo Peretti1, Bernard Kawa Kac1, Luna Azulay-Abulafia1.
Abstract
Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in a large number of untreated patients. Systemic corticosteroid therapy is considered first-line therapy. Adjuvant treatment with the goal of sparing corticosteroids include, among others, dapsone. This drug is not without side effects and its use requires clinical and laboratory control. We present a patient with PV initially managed with suboptimal dose of prednisone, evolving into drug-induced hepatitis after introduction of dapsone.Entities:
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Year: 2015 PMID: 26312673 PMCID: PMC4540507 DOI: 10.1590/abd1806-4841.20153408
Source DB: PubMed Journal: An Bras Dermatol ISSN: 0365-0596 Impact factor: 1.896