Literature DB >> 26310685

Are there reliable indicators predicting post-operative complications in acute appendicitis?

Juma Obayashi1, Kei Ohyama1, Shutaro Manabe1, Kunihide Tanaka1, Hideki Nagae1, Hideki Shima1, Shigeyuki Furuta1, Munechika Wakisaka1, Hirokazu Kawase1, Hiroaki Kitagawa2.   

Abstract

PURPOSE: To clarify the predictors of post-operative complications of pediatric acute appendicitis.
METHODS: The medical records of 485 patients with acute appendicitis operated on between January 2006 and November 2014 were retrospectively reviewed. Age, sex, preoperative WBC, CRP, and appendix maximum short diameter on diagnostic imaging (AMSD) were compared retrospectively with the complications group (Group C) vs the non-complication group (Group NC) by Student's T test, Fisher exact test and Multivariate analysis. Regression analysis with p less than 0.01 was considered significant. We analyzed the most recent 314 laparoscopic appendectomy patients similarly.
RESULTS: Complications were found in 29 of the 485 appendectomies (6.0%). Comparing Group C to Group NC, preoperative WBC (×10(3)/μl) 16.4 ± 5.6 vs 14.1 ± 4.1 (p < 0.01), CRP (mg/dl) 8.3 ± 7.1 vs 3.3 ± 4.6 (p < 0.01), AMSD (mm) was 12.1 ± 3.7 vs 9.9 ± 2.8 (p < 0.01). The CRP was significantly different by Multivariate analysis, but the WBC and AMSD wasn't. The results following laparoscopic appendicectomy data were identical.
CONCLUSION: Preoperative WBC, CPR and AMSD all indicated an increased risk of complications. If WBC (/μl) >16,500, CRP >3.1 mg/dl and AMSD >11.4 mm, complications increased sixfold.

Entities:  

Keywords:  Abdominal abscess; Acute appendicitis; Complication; Wound infection

Mesh:

Year:  2015        PMID: 26310685     DOI: 10.1007/s00383-015-3786-9

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  8 in total

1.  Perforated versus nonperforated acute appendicitis: accuracy of multidetector CT detection.

Authors:  Sarah D Bixby; Brian C Lucey; Jorge A Soto; Jens M Theysohn; Jens M Theyson; Al Ozonoff; Jose C Varghese
Journal:  Radiology       Date:  2006-12       Impact factor: 11.105

2.  Risk factors for the development of abdominal abscess following operation for perforated appendicitis in children: a multicenter case-control study.

Authors:  Marion C W Henry; Angela Walker; Bonnie L Silverman; Gerald Gollin; Saleem Islam; Karl Sylvester; R Lawrence Moss
Journal:  Arch Surg       Date:  2007-03

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Authors:  R H Pearl; D A Hale; M Molloy; D C Schutt; D P Jaques
Journal:  J Pediatr Surg       Date:  1995-02       Impact factor: 2.545

Review 4.  Appendicitis at the millennium.

Authors:  B A Birnbaum; S R Wilson
Journal:  Radiology       Date:  2000-05       Impact factor: 11.105

5.  The preoperative serum C-reactive protein level is a useful predictor of surgical site infections in patients undergoing appendectomy.

Authors:  Takayuki Shimizu; Mitsuru Ishizuka; Keiichi Kubota
Journal:  Surg Today       Date:  2014-12-06       Impact factor: 2.549

6.  Perforated appendicitis in children: risk factors for the development of complications.

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Journal:  Surgery       Date:  1998-10       Impact factor: 3.982

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Journal:  Ann Surg       Date:  1981-02       Impact factor: 12.969

8.  Appendicitis 2000: variability in practice, outcomes, and resource utilization at thirty pediatric hospitals.

Authors:  Kurt Newman; Todd Ponsky; Kory Kittle; Lorna Dyk; Cheri Throop; Karen Gieseker; Marion Sills; James Gilbert
Journal:  J Pediatr Surg       Date:  2003-03       Impact factor: 2.545

  8 in total
  5 in total

1.  Rapid non-contrast magnetic resonance imaging for post appendectomy intra-abdominal abscess in children.

Authors:  Megan H Lee; Eric P Eutsler; Elizabeth F Sheybani; Geetika Khanna
Journal:  Pediatr Radiol       Date:  2017-04-20

Review 2.  Pediatric appendicitis: state of the art review.

Authors:  Rebecca M Rentea; Shawn D St Peter; Charles L Snyder
Journal:  Pediatr Surg Int       Date:  2016-10-14       Impact factor: 1.827

3.  The effect of the broad-spectrum antibiotics for prevention of postoperative intra-abdominal abscess in pediatric acute appendicitis.

Authors:  Juma Obayashi; Shigeyuki Furuta; Takuya Kawaguchi; Kohei Kawaguchi; Kei Ohyama; Hideki Nagae; Munechika Wakisaka; Hiroaki Kitagawa
Journal:  Pediatr Surg Int       Date:  2018-08-14       Impact factor: 1.827

4.  Predictive Factors to Distinguish Between Patients With Noncomplicated Appendicitis and Those With Complicated Appendicitis.

Authors:  Tae Hyung Kim; Byung Sun Cho; Jae Hag Jung; Moon Soo Lee; Je Ho Jang; Chang Nam Kim
Journal:  Ann Coloproctol       Date:  2015-10-31

5.  The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis.

Authors:  Suqin Liu; Fenghua Pei; Xinhong Wang; Deliang Li; Lixia Zhao; Yanyan Song; Zhendong Chen; Bingrong Liu
Journal:  Oncotarget       Date:  2017-03-15
  5 in total

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