Literature DB >> 26308303

The Ups and Downs of TORKinibs in Transplantation.

Daniel Fantus1, Angus W Thomson.   

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Year:  2015        PMID: 26308303      PMCID: PMC4552074          DOI: 10.1097/TP.0000000000000803

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


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  5 in total

1.  Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation.

Authors:  Jianjun Zhu; Tianfei Lu; Shi Yue; Xiuda Shen; Feng Gao; Ronald W Busuttil; Jerzy W Kupiec-Weglinski; Qiang Xia; Yuan Zhai
Journal:  Transplantation       Date:  2015-01       Impact factor: 4.939

2.  Requirement for Rictor in homeostasis and function of mature B lymphoid cells.

Authors:  Keunwook Lee; Lindsey Heffington; Julia Jellusova; Ki Taek Nam; Ariel Raybuck; Sung Hoon Cho; James W Thomas; Robert C Rickert; Mark Boothby
Journal:  Blood       Date:  2013-08-19       Impact factor: 22.113

3.  mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.

Authors:  Jose J Limon; Lomon So; Stefan Jellbauer; Honyin Chiu; Juana Corado; Stephen M Sykes; Manuela Raffatellu; David A Fruman
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-10       Impact factor: 11.205

4.  Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signaling.

Authors:  Toshiyuki Yano; Marcella Ferlito; Angel Aponte; Atsushi Kuno; Tetsuji Miura; Elizabeth Murphy; Charles Steenbergen
Journal:  Circ Res       Date:  2014-02-20       Impact factor: 17.367

5.  mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.

Authors:  Hu Zeng; Kai Yang; Caryn Cloer; Geoffrey Neale; Peter Vogel; Hongbo Chi
Journal:  Nature       Date:  2013-06-30       Impact factor: 49.962

  5 in total
  3 in total

Review 1.  New perspectives on mTOR inhibitors (rapamycin, rapalogs and TORKinibs) in transplantation.

Authors:  Matthias Waldner; Daniel Fantus; Mario Solari; Angus W Thomson
Journal:  Br J Clin Pharmacol       Date:  2016-03-06       Impact factor: 4.335

2.  Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells.

Authors:  Enzo Candia; Paz Reyes; Camila Covian; Francisco Rodriguez; Nicolas Wainstein; Jorge Morales; Claudio Mosso; Mario Rosemblatt; Juan Alberto Fierro
Journal:  PLoS One       Date:  2017-07-26       Impact factor: 3.240

3.  Drug repurposing: Ibrutinib exhibits immunosuppressive potential in organ transplantation.

Authors:  Qing Zhang; Jicheng Chen; Hanchao Gao; Song Zhang; Chengjiang Zhao; Cuibing Zhou; Chengjun Wang; Yang Li; Zhiming Cai; Lisha Mou
Journal:  Int J Med Sci       Date:  2018-07-13       Impact factor: 3.738

  3 in total

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