Matti Lehtinen1, Dan Apter. 1. University of Tampere, and Family Federation of Finland, Finland.
Abstract
PURPOSE OF REVIEW: This review summarize the impact of various strategies of human papillomavirus (HPV) vaccination, such as vaccinating only girls or both girls and boys. RECENT FINDINGS: Slow and inefficient implementation of HPV vaccination programmes has delayed the impact of the first human cancer vaccine. Vaccinating only girls, with a rather low coverage, has led to a limited herd effect and, thus, not full use of the HPV vaccine potential. SUMMARY: Gender-neutral vaccination based on comparative effectiveness research will hopefully soon tackle the whole spectrum of HPV cancers in both sexes. The remaining challenges are how to ensure resilience of HPV vaccine-induced immunity and herd effect to guarantee population-level impact of HPV vaccination, and how to guard against HPV type replacement.
PURPOSE OF REVIEW: This review summarize the impact of various strategies of human papillomavirus (HPV) vaccination, such as vaccinating only girls or both girls and boys. RECENT FINDINGS: Slow and inefficient implementation of HPV vaccination programmes has delayed the impact of the first humancancer vaccine. Vaccinating only girls, with a rather low coverage, has led to a limited herd effect and, thus, not full use of the HPV vaccine potential. SUMMARY: Gender-neutral vaccination based on comparative effectiveness research will hopefully soon tackle the whole spectrum of HPV cancers in both sexes. The remaining challenges are how to ensure resilience of HPV vaccine-induced immunity and herd effect to guarantee population-level impact of HPV vaccination, and how to guard against HPV type replacement.
Authors: E D Moreira; A R Giuliano; J de Hoon; O-E Iversen; E A Joura; J Restrepo; P Van Damme; C Vandermeulen; M C Ellison; A Krick; C Shields; B Heiles; A Luxembourg Journal: Hum Vaccin Immunother Date: 2017-12-14 Impact factor: 3.452
Authors: Ángela María Ruiz-Sternberg; Edson D Moreira; Jaime A Restrepo; Eduardo Lazcano-Ponce; Robinson Cabello; Arnaldo Silva; Rosires Andrade; Francisco Revollo; Santos Uscanga; Alejandro Victoria; Ana María Guevara; Joaquín Luna; Manuel Plata; Claudia Nossa Dominguez; Edison Fedrizzi; Eugenio Suarez; Julio C Reina; Misoo C Ellison; Erin Moeller; Michael Ritter; Christine Shields; Miguel Cashat; Gonzalo Perez; Alain Luxembourg Journal: Papillomavirus Res Date: 2017-12-19