Peta Tehan1, Alan Bray2, Ruth Keech2, Richard Rounsley2, Angela Carruthers2, Vivienne Helaine Chuter2. 1. School of Health Sciences, Faculty of Health, University of Newcastle, Ourimbah, New South Wales, Australia (P.T., V.H.C.); and Vascular Health Care, Gateshead, New South Wales, Australia (A.B., R.K., R.R., A.C.). peta.craike@newcastle.edu.au. 2. School of Health Sciences, Faculty of Health, University of Newcastle, Ourimbah, New South Wales, Australia (P.T., V.H.C.); and Vascular Health Care, Gateshead, New South Wales, Australia (A.B., R.K., R.R., A.C.).
Abstract
OBJECTIVES: The toe-brachial index (TBI) is an alternative to the ankle-brachial index (ABI) in screening for peripheral arterial disease (PAD); however, there is limited evidence comparing their diagnostic accuracy. This study compared the diagnostic accuracy of the ABI and TBI in a population at risk of PAD. METHODS: The sensitivity and specificity of the ABI and TBI were determined by color duplex sonography. Receiver operating characteristic (ROC) analysis was performed. RESULTS: A total of 119 participants were recruited (75 male and 44 female). The sensitivity for PAD was highest for the TBI (71%; ABI, 45%), and the specificity was highest for the ABI (93%; TBI, 78%). Receiver operating characteristic analysis indicated that the TBI (ROC area, 0.77; P = .0001) had greater clinical efficacy for diagnosis of PAD than the ABI (ROC area, 0.65; P = .005). CONCLUSIONS: In specific populations, the TBI may have greater clinical efficacy than the ABI for diagnosis of PAD.
OBJECTIVES: The toe-brachial index (TBI) is an alternative to the ankle-brachial index (ABI) in screening for peripheral arterial disease (PAD); however, there is limited evidence comparing their diagnostic accuracy. This study compared the diagnostic accuracy of the ABI and TBI in a population at risk of PAD. METHODS: The sensitivity and specificity of the ABI and TBI were determined by color duplex sonography. Receiver operating characteristic (ROC) analysis was performed. RESULTS: A total of 119 participants were recruited (75 male and 44 female). The sensitivity for PAD was highest for the TBI (71%; ABI, 45%), and the specificity was highest for the ABI (93%; TBI, 78%). Receiver operating characteristic analysis indicated that the TBI (ROC area, 0.77; P = .0001) had greater clinical efficacy for diagnosis of PAD than the ABI (ROC area, 0.65; P = .005). CONCLUSIONS: In specific populations, the TBI may have greater clinical efficacy than the ABI for diagnosis of PAD.
Authors: Ali F AbuRahma; Elliot Adams; Joseph AbuRahma; Luis A Mata; L Scott Dean; Cristyn Caron; Jennifer Sloan Journal: J Vasc Surg Date: 2019-08-27 Impact factor: 4.268