Literature DB >> 26306852

Phosphatidylcholine's functions beyond that of a membrane brick.

Samuel Furse1, Anton I P M de Kroon1.   

Abstract

Since its discovery in the 19th century, phosphatidylcholine (PC) has been regarded primarily as a structural lipid. However, more recent evidence, much of it in the last five years, strongly suggests that PC has other roles. Here, we explore some of that new evidence and consider the possibility that the ultimate role of phosphatidylcholine may not be predictable.

Entities:  

Keywords:  Lipid isoforms; lipid signalling; phosphatidylcholine

Mesh:

Substances:

Year:  2015        PMID: 26306852     DOI: 10.3109/09687688.2015.1066894

Source DB:  PubMed          Journal:  Mol Membr Biol        ISSN: 0968-7688            Impact factor:   2.857


  33 in total

1.  Identification of cadmium-produced lipid hydroperoxides, transcriptomic changes in antioxidant enzymes, xenobiotic transporters, and pro-inflammatory markers in human breast cancer cells (MCF7) and protection with fat-soluble vitamins.

Authors:  Wageh Sobhy Darwish; Zhen Chen; Yonghan Li; Yue Wu; Hitoshi Chiba; Shu-Ping Hui
Journal:  Environ Sci Pollut Res Int       Date:  2019-11-25       Impact factor: 4.223

2.  Evolution of the Phosphatidylcholine Biosynthesis Pathways in Green Algae: Combinatorial Diversity of Methyltransferases.

Authors:  Takashi Hirashima; Masakazu Toyoshima; Takashi Moriyama; Naoki Sato
Journal:  J Mol Evol       Date:  2018-01-12       Impact factor: 2.395

3.  Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells.

Authors:  Katharina Koch; Rudolf Hartmann; Friederike Schröter; Abigail Kora Suwala; Donata Maciaczyk; Andrea Caroline Krüger; Dieter Willbold; Ulf Dietrich Kahlert; Jaroslaw Maciaczyk
Journal:  Oncotarget       Date:  2016-11-08

4.  The human plasma-metabolome: Reference values in 800 French healthy volunteers; impact of cholesterol, gender and age.

Authors:  Séverine Trabado; Abdallah Al-Salameh; Vincent Croixmarie; Perrine Masson; Emmanuelle Corruble; Bruno Fève; Romain Colle; Laurent Ripoll; Bernard Walther; Claire Boursier-Neyret; Erwan Werner; Laurent Becquemont; Philippe Chanson
Journal:  PLoS One       Date:  2017-03-09       Impact factor: 3.240

5.  Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study.

Authors:  Elin Rebecka Carlsson; Kristine H Allin; Sten Madsbad; Mogens Fenger
Journal:  Lipids Health Dis       Date:  2019-09-05       Impact factor: 3.876

6.  Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts.

Authors:  Valentina Agnusdei; Sonia Minuzzo; Marica Pinazza; Alessandra Gasparini; Laura Pezzè; Adriana Agnese Amaro; Lorenza Pasqualini; Paola Del Bianco; Martina Tognon; Chiara Frasson; Pietro Palumbo; Yari Ciribilli; Ulrich Pfeffer; Massimo Carella; Alberto Amadori; Stefano Indraccolo
Journal:  Haematologica       Date:  2019-08-29       Impact factor: 9.941

7.  The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain.

Authors:  Christoph Heier; Benedikt Kien; Feifei Huang; Thomas O Eichmann; Hao Xie; Rudolf Zechner; Ping-An Chang
Journal:  J Biol Chem       Date:  2017-09-07       Impact factor: 5.157

8.  Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism.

Authors:  Samuel Furse; Stuart G Snowden; Laurentya Olga; Philippa Prentice; Ken K Ong; Ieuan A Hughes; Carlo L Acerini; David B Dunger; Albert Koulman
Journal:  Sci Rep       Date:  2019-10-04       Impact factor: 4.379

9.  Metabolomics: a search for biomarkers of visceral fat and liver fat content.

Authors:  Sebastiaan Boone; Dennis Mook-Kanamori; Frits Rosendaal; Martin den Heijer; Hildo Lamb; Albert de Roos; Saskia le Cessie; Ko Willems van Dijk; Renée de Mutsert
Journal:  Metabolomics       Date:  2019-10-05       Impact factor: 4.290

10.  Identification of potential lipid biomarkers for active pulmonary tuberculosis using ultra-high-performance liquid chromatography-tandem mass spectrometry.

Authors:  Yu-Shuai Han; Jia-Xi Chen; Zhi-Bin Li; Jing Chen; Wen-Jing Yi; Huai Huang; Li-Liang Wei; Ting-Ting Jiang; Ji-Cheng Li
Journal:  Exp Biol Med (Maywood)       Date:  2020-11-11
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